🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Just presented at TCT and published in NEJM by Philippe Genereux showing superiority of early TAVR in asymptomatic severe AS. This trial will change the guidelines !

Among patients with asymptomatic severe aortic stenosis and myocardial fibrosis, early aortic valve intervention did not improve clinical outcomes compared with guideline-directed conservative management. #TCT2024 ja.ma/40ioKJy

The EVOLVED study w surgery/#TAVR in asymptomatic severe Aortic Stenosis w fibrosis on #whycmr JAMA - i guess results will be debated! But certainly early treatment not harmful. C together w EARLY TAVR! jamanetwork.com/journals/jama/… #TCT2024 Mamas A. Mamas Dr. Martha Gulati ♥️🫀❤️‍🩹🇨🇦

EVOLVED trial shows early intervention in pts with asymptomatic severe AS and myocardial fibrosis reduces hospitalization rates, favorable implications on quality of life. Watch full interview with Dr. Dweck clinicaltrialresults.org/marc-dweck-and… #TCT2024

Ongoing debate about the EARLY-TAVR primary endpoint, but after 3 days have found Suppl.Figure 4 - All-cause death, stroke, v.robust definition of HF hospitalization. HR 0.60 [0.44 - 0.83] - a positive trial! Benoy Shah MD Vass Vassiliou David J. Cohen, MD, MSc Philippe Genereux @mmamas19731

#AHA24: How does OxPL-apoB affect the risk of calcific aortic valve disease? Using data from MESA, Drs. Harpreet Bhatia, Sam Tsimikas, MD & team show that ⬆️ OxPL-apoB is associated with increased incidence and progression of valve disease bit.ly/3YRMeDf #JACC

Big news today on Sam Tsimikas and aortic stenosis. I will cover this in a brief tweetorial when I get a chance later today. Harpreet Bhatia UC San Diego Cardiology Fellows UC San Diego Cardiology

Our new paper suggests that OxPL-apoB may be an independent therapeutic target for calcific aortic valve disease UC San Diego Cardiology UC San Diego Cardiology Fellows UC San Diego Health Sciences I will also be presenting this work at #AHA24 on Monday

#AHA24 ICYMI: #JACC AE Dr. Marc Bonaca MD MPH and Dr. Sam Tsimikas, MD discuss new insights from the MESA cohort about OxPL-apoB and risk for calcific aortic valve disease 👇 📄: bit.ly/3YRMeDf

#EHJCVI 🛏️ Systemic hand-held echocardiography in patients hospitalized with #ACS #Echofirst #POCUS ✅ Agreement with #TTE ⏱️ 7.7 min 📊 Changed the clinical management plan in 42% 🫀 Sufficient for decision-making in 85% cases Read more 👉 doi.org/10.1093/ehjci/…

In moderate #aorticstenosis & asymptomatic severe AS, increased diffuse myocardial interstitial fibrosis on #whyCMR is associated with worse outcomes. jacc.org/doi/10.1016/j.… #JACCIMG #vhdAS #CMR Philippe Pibarot Labo Dr Clavel

Pleasantly surprised (and honoured!) to see this fantastic podcast covering our recent FAPI PET/MR publication from JACC Journals and Professor Valentin Fuster. Listen to his take here: jacc.org/digital-conten… And read our paper here: jacc.org/doi/10.1016/j.…

Patients with severe aortic stenosis who underwent aortic valve replacement exhibited similar extracellular volume fraction between sexes, while women had lower late gadolinium enhancement. ja.ma/3CSIQRx

Machine diagnosis of AS like an #EchoFirst maven? Using routine echo parameters a #deeplearning-based assessment of diastolic dysfunction can quantify the underlying milieu assoc w/ the latent risk of development & progression of severe AS. jacc.org/doi/10.1016/j.… #JACCIMG #vhdAS

In this meta-analysis of 4 RCTs, early AVR was assoc w/ a significant reduction in unplanned CV or #heartfailure hospitalization & #stroke & no differences in all-cause & CV mortality compared w/ clinical surveillance. jacc.org/doi/10.1016/j.… #JACC Philippe Genereux Marty Leon

🚨 Excited to share our work on #AI #DASSi phenotyping of #AS on 2D #EchoFirst: a low-cost surrogate for multimodality imaging in AS trials A fun collaboration between CarDS Lab Rohan Khera & The University of Edinburgh (Marc Dweck, Neil Craig et al) 🔗 Preprint + 🧵below #ACC25

And the morning concludes with Dr Neil Craig Neil Craig discussing Hybrid imaging of aortic stenosis followed by an enlightening panel session.

Delighted to share our findings on the impact of coronary CT angiography 🩻 on 🏃🏼‍♂️ 🍽️ 🚬 ⚖️ , acceptance of 💊 and risk factor modification compared to CV risk scores 🎯 in this SCOT-HEART2 substudy