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Based on the ECLIPSE trial, U.S. FDA today approved the Guardant SHIELD blood test for #ColorectalCancer. Matthew Herper in STAT statnews.com/2024/07/29/gua… See ECLIPSE data below & why individuals undergoing this assay should clearly understand - this is NOT a test for CRC

Vir Biotechnology announced today it's all but abandoning infectious disease research and pivoting to cancer. My story from May on how a grand, billion-dollar plan to build a company to create "a world without infectious disease" fell apart: statnews.com/2024/04/15/vir…

So sad to hear about the passing of Jeff Weber, a giant in the field of oncology. He was involved in the early days of cytokine and cell therapy and most recently led studies of personalized vaccines for melanoma patients. I originally worked with Jeff National Cancer Institute over 30 years ago.

Leading the American Cancer Society Society + American Cancer Society Cancer Action Network is the honor of a lifetime. Over the last 3.5 years, we increased our impact and focused on improving the lives of cancer patients. I love this org! With ACS on strong footing and having accomplished what I came to achieve, today I

I'm honored to present #SCLC updates at the 2nd annual Thomas C. Shea Clinical Cancer Symposium on Monday, September 23rd from the UNC Lineberger cancer center alongside Drs. Jared Weiss Dr. Julie Brahmer Mark Socinski Norman Sharpless and others! In person The Umstead Hotel and Spa in Cary, NC!

I'm excited to announce that @NCICCHE Director Dr. Sanya Springfield will be an acting deputy director at National Cancer Institute – in this new role, she'll be charged with broadening and strengthening our cancer health equity and inclusion efforts. #EndingCancerAsWeKnowIt for all.

An important study by F. Eun-Hyung Lee's team shows that long lived plasma cells (the source of long-term circulating antibodies) fail to establish after mRNA vaccination (even combined with SARS-CoV-2 infection). 🧵 (1/) nature.com/articles/s4159…

Out in JCO: the ratio of enrollment to Industry- vs Federally-sponsored trials doubled between 2008-2022. This led to an acceleration in drug development, but less trials exploring de-escalation or non-drug-related questions. Great editorial by Yara Abdou, MD, MSCR. ascopubs.org/doi/10.1200/JC…

Paolo Tarantino Yara Abdou, MD, MSCR Journal of Clinical Oncology A link to the editorial by Yara Abdou, MD, MSCR Norman Sharpless UNC Lineberger ascopubs.org/doi/full/10.12… worth reading!

The rise of industry-sponsored cancer clinical trial enrollment from 2008 to 2022, now surpassing NIH-sponsored trials, highlights a shift in oncology research priorities. This trend may limit opportunities for addressing broader, patient-centered questions that are not

A single-cell atlas of aging tissue demonstrates shared multi-omics of aging and cancer hallmarks nature.com/articles/s4358… Nature Aging The Jackson Laboratory @justsaysinmice @OlgaAnczukow

Novocure and its Tumor Treating Fields (TTF) Modality meets its Phase 3 trial primary endpoint of improving survival in local advanced #PancreaticCancer (LAPC). Caveats are several: - modest improvement in survival (one of those statistically significant but “is it meaningful”

Every year, ~90,000 teens and young adults receive a cancer diagnosis. Programs like those at UNC Lineberger—an NCI-Designated Comprehensive Cancer Center—help young people navigate treatment, enroll in trials, and get fertility counseling. Read more: go.nih.gov/spJyrrI

If we want to thoughtfully reduce NIH indirect costs, we need to reduce the federal regulatory burden that causes universities to hire so many administrators to remain compliant.

Time to re-up this. Congrats to Larry T on a great career at NIH. A wonderful Fed.

Nearly 100 NIH study sections were canceled in the past month. Here is a list of the canceled meetings, compiled by Annika Barber at Rutgers Univ. As a result, the process of biomedical science funding has been halted in the United States. tinyurl.com/5auw74s4

So what's happening with medical research in the US? This is the cumulative award count from the NIH for the year. Doesn't look so good. But it gets worse. 1/

How the NIH dominates the world’s health research — in charts. Great comments by Miriam Merad, MD, PhD nature.com/articles/d4158…

🧵 Twenty-five years ago, it was common to hear complaints about a “drug lag”—the perception that Europeans routinely enjoyed medical advances years before their American counterparts. Through a generation of congressional actions, investments in expertise and hiring, and careful

🤠 👉🏽 🗽 news: I will be joining NYU Langone Health on September 1, 2025 as Director of the GI Cancer Center & Associate Director of Translational Research at Perlmutter Cancer Center at NYU Langone Health. I am excited to start the next chapter of the Maitra Lab in NYC & build a strong GI cancer research program.