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We should get mad about the Spruce Hill historic neighborhood designation—effectively a permanent downzoning for one of Philadelphia's wealthiest neighborhoods. This will exacerbate rising rents, displacement risk, and development pressure elsewhere in West Philly.

I want to highlight *some* of my favorite studies on dendrites and spines from 2024 👀 - feeling very excited and inspired about the field 🔥 Happy new year y'all!

TOMORROW… MetroRewind.com #wmata

Imagine running a restaurant & suddenly only having budget for ingredients & chefs—no rent, electricity, heat, water, support staff, insurance, trash, toilet paper. This is what 'cutting indirects' did to every major biomedical center & hospital in the US.

Gentrification is when they build $3,000/month apartments in a neighborhood where single family homeowners are making $5,000/month mortgage payments.

As we speak, scientisists across the country (including myself) are trying to to take care of simple administrative tasks related to the grants that we have recieved from the National Institutes of Health... 1/n

Now in Cell: K+ ion channels enable electric currents consisting of potassium ions to generate action potentials in heart, brain, and muscle. For the first time, we can now see these currents atom-by-atom. cell.com/cell/abstract/… a thread🧵 1/8

"In D.C., no driver has been charged in any of the 15 fatal hit-and-run crashes of 2024." washingtonpost.com/dc-md-va/2025/…

Congestion pricing turns travel time tolls into money tolls Time losses are pure waste; money tolls raise revenue. It's like alchemy, turning lead into gold! This is not just a clever metaphor, it's literally true & is why NYC's business community has relentlessly supported it

love this city

The US produces huge, heavy cars which cost more, require more land and infrastructure, and produce more noise & air pollution, brake and tire particulates (GHG, microplastics). The weight/height is a key contributor to our insane and increasing rate of road deaths and injuries.

Wow! Each $1 spent on Universal Pre-Kindergarten generates between $3-$20 dollars in aggregate earnings. That's enough to offset the costs of Universal Pre-Kindergarten through higher tax revenues.

Mayor Scott and YIMBY leaders on the City Council introduced bills today that would roll back Baltimore's restrictions on development density, allow people to build closer to their property lines, and do away with requirements for off-street parking thebaltimorebanner.com/community/hous…

1/12. How do cortical interneurons select specific pyramidal cells during development? Julie Jezequel in Beatriz Rico has identified specific cellular and molecular codes that interneurons use to target pyramidal cell types Nature Communications CDN | King's College CNDD| King's College Institute of Psychiatry, Psychology & Neuroscience

CHOP & Penn Medicine have delivered the first-ever personalized gene editing therapy for a patient with CPS1 deficiency, marking a major milestone in the application of CRISPR-based treatments. Learn more about KJ & the future of personalized medicine: ms.spr.ly/6015SZLAx.

.City of Portland, Maine’s 2024 Housing Report confirms what many feared: raising IZ from 10% to 25% in 2021 didn’t spark affordability — it torched production. From 900+ units in 2021 to barely a trickle since. Inclusionary zoning with exclusionary results.

Incredibly bad (changes to N.S.F. funding for math):

From here: nytimes.com/interactive/20…

Biomolecular condensates organize cellular contents. Most studies focus on passive phase separation, driven by salt, pH, or temperature. But what if intracellular movement also matters? science.org/doi/10.1126/sc… Here, we explore motility-induced condensation in a cellular context.