2025 = 45^2 It's a perfect square. It will probably be the only perfect square year you ever get to live in. The last time that occurred was in 1936. The next will be in 2116. So, make 2025 a perfect year for you.

It’s like most people never heard of project based learning, there’s a github repository on how to make anything without knowing anything github.com/practical-tuto…

Extreme regulations about data sharing risk leaving Europe behind in the precision medicine race❗️🧬 GDPR is interpreted differently by each EU state-member🇪🇺 Cross-border data sharing restrictions often kill collaborative projects, despite researchers' best intentions.

BREAKING: Trump has imposed 25% tariffs on the import of all Python libraries, with an extra 10% on NumPy

Language Models Use Trigonometry to Do Addition "We first discover that numbers are represented in these LLMs as a generalized helix, which is strongly causally implicated for the tasks of addition and subtraction, and is also causally relevant for integer division,

It was super fun working on Evo 2, a DNA language model trained on genomes across the tree of life! Check out the preprint: arcinstitute.org/manuscripts/Ev… A small 🧵 highlighting some mechanistic interpretability work on Evo 2 (Fig. 4) we did in collaboration with Goodfire 🔥🔥🔥

Today I was sent the following cool demo: Two AI agents on a phone call realize they’re both AI and switch to a superior audio signal ggwave

changing github . com to uithub . com gives you the whole code repo and structure so you can pass to an LLM

It’s official. We have launched! 🚀 ⁦npj Journals⁩ ⁦UCSF MAC⁩ ⁦Global Brain Health Institute⁩ 🧠 🌍 npj Dementia: Transformative research, global perspectives | npj Dementia nature.com/articles/s4440…

Google's global PhD Fellowship Program will open for applications on April 10, 2025. This program supports exceptional PhD students in computer science and related fields, providing a Google Research Mentor. We welcome applications in areas including Machine Learning, Natural

Wow! 🍷✅ 🍺❌

"Mathematics should be accessible to everyone." Meanwhile, mathematicians:

I'm prototyping a little tool for interactively visualizing the near-nearest neighbor network in single-cell RNA-seq. Clicking a cell triggers a wave, revealing its nearest neighbors, then their neighbors, and so forth. Data: 10k PBMCs from a Healthy Donor (v3), 10x Genomics

90% of doing science is being open to new ideas.

X chromosome dosage compensation through the lens of human genetics! Females have two X chromosomes, but males have one. To compensate for this, one X is randomly inactivated in female cells. Some genes escape from this inactivation. Because both males and females are

Direct detection of 8-oxo-dG using nanopore sequencing. #DNAmodifications #Nanopore #Sequencing Oxford Nanopore Nature Communications nature.com/articles/s4146…

In this fascinating preprint, the authors uncover an eye-opening feature of tRNA genes: they’re insanely prone to mutation. Analyzing somatic mutations in cancer tissues, they report that tRNA genes are up to 9 times more mutated than protein-coding genes. Interestingly, the

Alzheimer's disease (AD) risk at various polygenic score (PGS) percentiles compared to median group (40-60%). In addition to APOE, other risk variants as well contribute significantly to AD risk, independent of APOE (but clearly APOE is the single most important risk factor in