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Great video from the Ramon y Cajal of brain mapping in the genetics era: Ed Lein. Amazing facts on the human brain map from the video: At least 3,000 cell types and much of that diversity is not in neocortex. Beautiful!

Beautiful new work on gene therapy for Dravet (SCNA1A)!

Our lab generated 4 new lines of Cas12a transgenic mice and demonstrated utility in immune engineering, tumor modeling, and genetic disease treatment. Around to share w the field & community! Yale School of Medicine Yale West Yale Department of Genetics Yale Center for Biomedical Data Science (CBDS) Also Monte Winslow's Lab nature.com/articles/s4155…

During graduate school, I read many textbooks but the clearest and best one by far was Steven Strogatz 's Nonlinear Dynamics and Chaos. Important to see that — like with everything in life — it's just about working at it, getting better and not giving up!

Amazing addition to NY Genome Center — very lucky to have a pioneer in functional genomics joining us. Welcome Bing! 🚀🚀🚀

And also some experiments from our lab NY Genome Center and New York University (led by #ChristinaCaragine) — good luck to the fram2 on their return to Earth in the next day or two!

"Here’s a contrarian take. It’s better to get AI engineers excited to work on the audacious goals of advancing human health vs. working on chatbots, customer support agents, and agent infrastructure" - Patrick Hsu Agree — 100%! (and this is a great interview)

What wonderful news — great to see more and more benefits of gene editing therapies 🚀

Fantastic interview. In the NYT interview, Rutger Bregman also mentions abolitionist Thomas Clarkson (who had a fascinating life: en.wikipedia.org/wiki/Thomas_Cl…) and who was also in the news this week about the discovery of an original Magna Carta: hls.harvard.edu/today/harvard-…

“This is reality; it’s not science fiction. We’re actually doing it. I’ve had patients of mine in the trial receive this one-and-done treatment, and it’s going to change the face of cholesterol management going forward.” sciencefocus.com/news/new-chole…

The micropipette—that ubiquitous tool found in laboratories around the world—was invented by a 32-year-old German postdoc in 1957 after a particularly productive two-day tantrum. That first device, made by Heinrich Schnitger, had “all the essential features of the modern

Amazing work from former lab member Joshua Meier on AI-enabled, one-shot protein design. Go Josh & Chai Discovery ! 🚀

Beautiful deep dive from Sri on what it means to predict cell behavior (/virtual cell /foundation model). Great Sunday read with references to Brenner, Ptashne, Arkin and many others.