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Back to the Plant Energy Biology Lab roots for international plant science meeting 2024 #Oxford #plantcomm #networking #birthday #25 #Schachtelkranz Lena Knorr Jan-Ole Niemeier @jan_multhoff

Just out in JXB @jxbotany.bsky.social: glutathione redox biosensing in barley – a first in cereal crops! 🌾🔬 Door opener led by Finja & Stefanie Müller to get to the bottom of crop stress responses. Ivan F. Acosta Andreas Meyer Frank Hochholdinger image cred Jan-Ole Niemeier & Pedro doi.org/10.1093/jxb/er…

Another fantastic screening Plant Energy Biology Lab with Ana Furlanetto 🌱🔬

Wer im EU-Parlament hört auf die Wissenschaft, wenn es um Neue Gentechnik geht und wer nicht? Hier das Wahlverhalten unserer deutschen Parlamentarier: 👇

Our lab's first venture into the world of social media! I am happy to share our new preprint on novel NADP redox sensors: biorxiv.org/content/10.110…

🎉 Exciting News 🎉 🧬 Our latest preprint on the NAPstar family of NADP redox state biosensors is out! A game-changer in understanding cellular redox dynamics. Let's dive in! #ScienceTwitter #RedoxBiology International Society for Plant Low O2 Research Europe-SFRR

1/ 🚀 Introducing NAPstars: a novel family of genetically encoded, fluorescent biosensors designed to illuminate the NADPH/NADP+ redox couple's role in metabolism and signaling at unprecedented resolution. Full details here: biorxiv.org/content/10.110…

2/ 🧪 Developed through a long-term collaboration between Morgan_lab and Plant Energy Biology Lab, the NAPstars represent a milestone in rational biosensor engineering. A true team effort with the joint goal of pushing the boundaries of our understanding of how cells really work.

3/ 🔬 Why NAPstars? Until now, getting a clear view of the NADP redox state across subcellular compartments was a major challenge. NAPstars offers real-time, specific, and pH-resistant measurements, providing insights that no existing tool can provide.

4/ 🌱🐁 From yeast to plants to mammalian cells, NAPstars have proven their versatility and robustness, revealing critical insights into how cells maintain redox homeostasis and respond to environmental cues like light and oxygen levels.

5/ 💡 One of several striking findings? The central role of glutathione as the primary mediator of anti-oxidative electron flux across different organisms. This challenges existing views and opens new avenues for research in redox biology.

6/ 🔄 We've observed NADP, NAD and H2O2 redox oscillations linked to the cell cycle in yeast and how plant leaves adjust their redox state in response to changes in light and oxygen. This level of detail was previously unimaginable.

8/ 🙏 A huge shoutout to our teams with Marie and Jan-Ole Niemeier as co-leads, our students and collaborators. Christopher Bell Johanna B Kroll @s_lichtenauer @jan_multhoff Messens Lab Jan Riemer

8/ 🚀 This is just the beginning, and we're excited to see where NAPstars will lead us all! 🔗 Again, here's the link to our preprint for a deep dive into our research: biorxiv.org/content/10.110…

Jan-Ole Niemeier finishing the session with a nice talk about the importance of study redox biology upstream of Cysteines with their newly NADPH:NADP+ sensors. Preprint available here: biorxiv.org/content/10.110…

What's your favourite central metabolite?🧑‍🔬 @jan_multhoff 's choise has been pyruvate! Thrilled to share his work on pyruvate biosensing in live leaf tissues🍃revealing remarkable dynamics at illumination🌤️ Jan-Ole Niemeier Zhengke JXB @jxbotany.bsky.social Universität Münster doi.org/10.1093/jxb/er…

Hildebrandt Lab Cell Physiology, Halle Finkemeier lab Joanna Chustecki @s_lichtenauer Jan-Ole Niemeier @jan_multhoff Stefanie Müller Dennis Brandt Jay Ieh

A new biosensor is born 👼 The NAPstar family for live NADP redox monitoring🔋🪫 Jointly with Morgan_lab & Jan Riemer Jan-Ole Niemeier looked in vitro, in yeast, plants & mammalian cells 🧪🦠🧫🌱 Where to go next? Nature Communications doi.org/10.1038/s41467…

Researchers have developed biosensors that can be used to measure the ratio of NADPH to NADP⁺ in living cells in real time for the first time. Universität Saarland Plant Energy Biology Lab Morgan_lab Jan-Ole Niemeier Jan Riemer Nature Communications doi.org/10.1038/s41467… & uni-muenster.de/news/view.php?…