ERJOR: In T2-biomarker-low severe asthma, participants with high symptom scores displayed increased urinary eicosanoid levels of thromboxanes and isoprostanes. These metabolites are potent bronchoconstrictors that can act on the thromboxane receptor. bit.ly/4hhK1ZB

New EMBARC paper published in The Lancet Respiratory Medicine Here is a thread on this paper led by Oriol Sibila and why the results are important for patients Symptoms, risk of future exacerbations and response to long term macrolide treatment in bronchiectasis

Treatment of Severe Asthma Is Not “Cookie-Cutter” Medicine American Thoracic Society (ATS) 🔓 Open Access 🔗 tinyurl.com/5n6zu9vj

Clinical Remission by a Comprehensive Severe Asthma Management Strategy Guided by Airway Inflammometry and Bioimaging Comprehensive management with airway inflammometry and bioimaging can increase clinical remission rates in severe asthma Santi Nolasco 🔗 tinyurl.com/ycy3ynjm

Our article is now in print in the September issue of the American Journal of Respiratory and Critical Care Medicine (#AJRCCM) ATS Blue Journal

The new edition of the ERS Handbook of Respiratory Medicine has arrived at the Publications Office and pre-ordered copies will be shipped this week

The Blue Journal thanks Santi Nolasco, MD, PhD, for his contribution to the September issue Clinical Remission by a Comprehensive Severe Asthma Management Strategy Guided by Airway Inflammometry and Bioimaging Santi Nolasco McMaster University Department of Medicine The Research Institute of St. Joe's Hamilton atsjournals.org/doi/full/10.11…

Delegation has been the most difficult part of being a PI for me - and finding amazing colleagues who are conscientious and skilled has been a game changer in recent years There is some useful stuff here Influence don’t control Teach what good looks like then give independence

Clinicians can enhance patient understanding by using numerical data instead of verbal probabilities, consistent denominators, absolute risk comparisons, and clear context for unfamiliar data types. ja.ma/4gJCCD6

Proud to share our recent work from the Southern Italy Network on Severe Asthma Therapy, now published in Allergy EAACI ! 🎉 We explored the Arg16Gly β2-receptor polymorphism and its impact on asthma severity, mepolizumab response & remission. 🔗 onlinelibrary.wiley.com/doi/10.1111/al…

Treatment of Severe Asthma Is Not “Cookie-Cutter” Medicine American Thoracic Society (ATS) 🔓 Open Access 🔗 tinyurl.com/5n6zu9vj

New Research: International healthcare workers report on war related injuries among civilians in Gaza Findings suggest patterns of harm that exceed those reported in previous modern day conflicts bmj.com/content/390/bm…

Honored to receive the ERS Mid-Career Gold Medal in Respiratory Intensive Care! Excited to keep contributing to the field and to the community that made this achievement possible. #ERS #ERSassembly2 #RespiratoryCare #RespiratoryIntensiveCare

#mdpijcm #Editor’s Choice Paper🔍 Citations 6👏 #Eosinophilic_Bronchiectasis: Prevalence, Severity, and Associated Features—A Cohort Study by Raffaele Campisi et al. Unict 👉mdpi.com/2921766 MDPI Medicine & Pharmacology

More progress with stem cells treating #Parkinsons disease, as seen by motor improvements in a dose-escalating study of 12 patients cell.com/cell/fulltext/…

#GLP1 medicines now address weight loss and other health conditions through innovative formulations and expanded indications, highlighting key questions about their efficacy and safety. ja.ma/4nHJMKw

One of the most important metric for deciding to start a patient on a new treatment is NNT (number-needed-to-treat). Here, Mohsen and I discuss NNT in the context of #dupilumab for #COPD. You will find out the difference btn event vs person-based NNT. bit.ly/3UGhumT

New in ERJ: The CANUCK Study examines how #Cannabis smoking affects the lungs. High cannabis exposure linked to: ↑ respiratory symptoms ↓ lung function ↑ emphysema & ventilation defects in imaging Airway immune & mucin gene dysregulation Read: doi.org/10.1183/139930…

ERJ Open Research: Cough-variant asthma exhibits overlapping but distinct airway transcriptomic profiles compared to classic asthma. Two distinct inflammatory endotypes of cough-variant asthma are identified, presenting different clinical outcomes. bit.ly/3Zmgjvs

Well, well, well. Who woulda thought that literally washing away germs mitigates illness. Glad to see this data. I’ll also take nasal rinses for $400.