
andre nussenzweig lab
@nussenza
Squash fiend and Scientist. All views are my own
ID: 1441000374
19-05-2013 12:10:28
466 Tweet
3,3K Followers
885 Following





Please RT and tell potential candidates: PhD student and postdoc position available in my lab to work on control of telomere maintenance by ALT in pediatric cancer and ways to exploit this in therapy (funded by KiKa). Email me at [email protected] to apply.

On our #NWO project, we're collaborating with Arnab Ray Chaudhuri to explore chromatin modifications at replication forks. For this joint PhD position, please send CV, motivation letter & two referees' contacts to [email protected]; [email protected] Help spread the word!🙏

It has been a long ride but our work on the essential role of Duxbl during the exit from totipotency is finally out in Nature Genetics rdcu.be/dBRPF nature.com/articles/s4158… x.com/sruizmacias/st…

We are looking for a postdoc to join us Johns Hopkins Medicine in beautiful (yes!) Baltimore, MD. Help us investigate the role of RNA and RNA/DNA secondary structures in DNA repair. Several CRISPR screen hits are waiting for follow-up analysis. Please RT! oberdoerfferp.wixsite.com/po-lab/positio…



A high-resolution view of how replication-coupled DNA breaks are generated, processed and repaired. Congrats to Raphael Pavani, Veenu Tripathi, and many terrific collaborators including Johannes Walter, Cejka Lab, Wei Wu. See science.org/doi/epdf/10.11…

With their help, we found formulations of engineered nanoparticles that can efficiently deliver Cas9 into (iPSC-derived) postmitotic human neurons. And cut open their DNA. @JiaChen98369353 from andre nussenzweig lab lab took pictures of these Cas9-induced breaks in our neurons’ DNA.



Check out our latest paper showing that HLTF removes Cas9 from DNA, explaining phenotypic differences when using the two Cas9 nickase variants. Important for gene editing! Thanks to Giordano Reginato & Rosaria and @MartinJinek Taekjip Ha andre nussenzweig lab nature.com/articles/s4146…



Congratulations The Fidock Lab, @GarciaLabMS, andre nussenzweig lab, @PappulabWashU & @RNHelsleyPhD! #ASBMB2025 #ASBMBAwardWinners

🚨 New publication in Molecular Cell ! We reveal STK19 as essential transcription-coupled DNA repair factor, stabilizing the TC-NER complex and enabling efficient RNA Pol II ubiquitylation & TFIIH recruitment. ➡️tinyurl.com/mtxt9rkk



Congratulations Sounak Sahu, Mélissa Galloux, members of our BRCA Variant Analysis Unit National Cancer Institute for this outstanding work. Sincere thanks to our collaborators Drs. Chari, Papaleo, Michailidou and their team members.

Excited to share our new paper on Nature - how Ku accommodates Alu expansion in primates by binding to dsRNA, providing a clue for both the high levels of Ku and its essentiality in human cells. Thank Chaolin Zhang Hachung Chung at Columbia University Lena Steckelberg More to come nature.com/articles/s4158…