Great to be part of this incredible SAH session at #ISC23 with Nima Etminan, Robert Loch Macdonald, #cenkayata Neurovascular Research Unit, Sherry Chou MD MSc FNCS FCCM, Charlene Ong, and Sepi Amin-Hanjani AHA Science eppro02.ativ.me/appinfo.php?pa…

Great to see our article on #pericyte control of blood flow in #brain and #heart out in Annual Reviews. The result of a great collaboration with the Lederer lab here at University of Maryland, Baltimore! annualreviews.org/doi/full/10.11…

#OriginalResearch: Optogenetic Spreading Depolarizations Do Not Worsen Acute Ischemic #Stroke Outcome #AHAJournals ahajrnls.org/41R4vAW David Chung Neurovascular Research Unit

#STROKE #OriginalResearch Spreading depolarizations decreased hematoma growth by >40% as a protective feedback mechanism after in murine intracerebral hemorrhage. ahajrnls.org/3P95VTc David Chung Takahiko Imai Neurovascular Research Unit Charité Experimental Neurology Berlin

Turkish coffee break! Our senior fellow and SPAN network coordinator Sanem Aykan is also an expert coffee ground reader. nvr.mgh.harvard.edu/staff/sanem-ay…

Happy to see the results of our Stroke Preclinical Assessment Network (SPAN)1 in ⁦Science Translational Medicine⁩ We (6 sites) performed 2615 rodent stroke surgeries, recorded/analyzed 1000s of behavior videos over the period of 3yrs ⁦@NINDSnews⁩ #TeamScience science.org/doi/10.1126/sc…

#Stroke October Cover Figure: Spreading depolarizations decrease hematoma growth by 40-60% as a protective feedback mechanism in murine intracerebral hemorrhage. #AHAJournals ahajrnls.org/3P95VTc David Chung Takahiko Imai Neurovascular Research Unit

I will do an oral presentation in Late Breaking Science in the International Stroke Conference 2024 #ISC24 AHA Science LB9 “Subgroup Analysis of Fasudil Efficacy in the Multi-Laboratory Stroke Preclinical Assessment Network Trial” professional.heart.org/en/meetings/in…

Our boss, Professor. Cenk Ayata is speaking about translation stroke research #ISC24 AHA Science

I’m done my 1st oral presentation in late breaking science! Thank you so much for giving me a great opportunity! #ISC24

Non-Invasive Vagal Nerve Stimulation Pre-Treatment Reduces Neurological Dysfunction After Closed Head Injury in Mice | Neurotrauma Reports liebertpub.com/doi/10.1089/ne…

Our lab’ researchers will join to Mass General Cancer Center 5k Eversource Run on September 15!🏃🏃‍♀️ Check out MGH Neurovascular Research Unit Run team's team fundraising page - because.massgeneral.org/team/588035

Latest results about SPAN! Congratulations Andréia Morais 🎉 Circulation Research Neurovascular Research Unit ahajournals.org/doi/10.1161/CI…

We published new paper about mouse stroke model!🎉 Hippocampal infarction and generalized seizures predict early mortality after endovascular middle cerebral artery occlusion in mice - ScienceDirect sciencedirect.com/science/articl…

5/5 Biological and Procedural Predictors of Outcome in the Stroke Preclinical Assessment Network (SPAN) Trial by Andréia Morais et al bit.ly/3WjgBRB Neurovascular Research Unit LaurenHSansing Nirav Dhanesha @alison_herman Takahiko Imai Mariia Kumskova Márcio Augusto Diniz

Lab member joined to race! MGH Cancer Center Eversource 5K

My paper has been published！JCBFM We investigated the effects of both non-selective (fasudil) and isoform-selective (NRL-1049) Rho kinase inhibitors in 🐀 intracranial hemorrhage model. Unfortunately, neither treatment showed significant efficacy. journals.sagepub.com/doi/abs/10.117…

#STROKE Simultaneous publication at #ISC25 🔴CADASIL mice showed impaired brain connectivity and motor function, highlighting challenges in treatment. Tocotrienol, a neuroprotective vitamin E derivative, failed to prevent disease progression on these metrics. 🐁

Our paper was published! JAHA We tested anti-inflammatory proteins efficacy in both transient and permanent stroke mouse models, mimicking previously published study designs and protocols to seek reproducibility. However, there was no efficacy. ahajournals.org/doi/10.1161/JA…

My 1st author paper was published in Stroke! We evaluated the efficacy of Rho kinase inhibitor, Fasudil on animal stroke models in Multi-center preclinical trial network (SPAN). Fasudil improved outcomes. Thank you so much for all SPAN members!㊗️🎉 ahajournals.org/doi/10.1161/ST…