Carter Bradley coming in at QB for #49ers opening drive of the second quarter.

#49ers S Marques Sigle questionable to return with knee injury.

Trent Sherfield Sr. Revenge game. The storyline overlooked all week.

Tre Brown is getting run with the third string defense at outside CB to open the third quarter. Quite a drop off from the guy working with the 1s early in camp at nickel and outside.

#49ere coach Kyle Shanahan says CB Upton Stout did not play tonight because he has tightness in his calf. Playing it safe per Shanahan.

It is indeed a hyperextended knee for #49ers DE Mykel Williams. He’s expected to miss a week, per Kyle Shanahan.

#49ers S Richie Grant did not play tonight because of a knee issue, per Kyle Shanahan. He’s expected to miss about a week, also.

Kyle Shanahan said initial indication was that knee injury to #49ers S Marques Sigle isn’t serious but still further testing to do to confirm that. Shanahan noted that Sigle played well before the knee issue.

#49ers activated OT Andre Dillard (ankle) from PUP list. He can begin practicing as soon as today.

Other #49ers moves: Signed - RB Jeff Wilson Jr., DL Trevis Gipson Placed on IR: RB Ameer Abdullah Waived: QB Tanner Mordecai

#49ers just wrapped up about an 80 minute practice. A lot of players missing today. I had 15 players not participating, not including the four others on PUP or NFI. Among those not playing: CB Upton Stout, WR Jordan Watkins, DE Robert Beal Jr. Only returnees: S Ji’Ayir Brown,

#49ers rookie WR Jordan Watkins has a high ankle sprain. He’s expected to miss about a month.

Still not a firm timeline but #49ers coach Kyle Shanahan estimates a possible Week 6 return for WR Brandon Aiyuk. Shanahan said it "could be week 10 or could be Week 5" noting that those things are fluid. Same for S Malik Mustapha.

STORY: #49ers take yet another hit at WR with Jordan Watkins suffering a high ankle sprain and uncertainty remains around Brandon Aiyuk, Jauan Jennings and Demarcus Robinson... espn.com/nfl/story/_/id…

Notes and observations from #49ers practice No. 13: - A relatively shot, 80-ish minute practice today. A bit of a warm day but it was light, largely because of the injuries. The Niners did no one on ones today and they modified the reps so the 2s and 3s were blended because of

#49ers off the practice field after a nearly 90 minute practice. Many still missing but WR Jacob Cowing did return from hamstring injury. Cowing did individual and a bit of team snaps though eased in there. Dominick Puni with the play of the day, catching a batted pass and

#49ers LG Ben Bartch departed practice midway through team period. Unclear why. Rookie Connor Colby stepped in for him to finish the session.

Notes and observations from #49ers practice No. 14: - An 87-minute practice for the Niners on a relatively warm day but with a lot of players still missing. For the second straight day, they skipped one on one drills, so most of the below is observed from team periods. - Here's

#49ers signed WR Malik Turner and placed DE Bradlee Anae on injured reserve.