YukinoriOkada
@okada_yukinori
Professor, Dep. Genome Informatics, The University of Tokyo
Professor, Dep. Statistical Genetics, Osaka University
Team Leader, Lab. Systems Genetics, RIKEN IMS
ID: 1175322065815031809
https://genome.m.u-tokyo.ac.jp/index.html 21-09-2019 08:13:22
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Grad to see our Comment about inconsistent embryo selection across PRS methods is out in Nature Human Behaviour! nature.com/articles/s4156… Thanks again to the great collab with specialists for genetics/ELSI Masato Akiyama, Kazuto Kato, Soichi Ogishima, Kyuto Sonehara, Kenichi_Yamamoto_Osk, YukinoriOkada
Please check our platform talk at #ASHG2024🎉 1. Deciphering genetic contribution of ancient hunter-gatherer Jomon in Japanese Populations, Kenichi_Yamamoto_Osk, Session 16. 2. Enhancing regulatory variant prioritization via long-range DNA seq and multi-task learning, Qingbo Seiha Wang, Session 73.
Thank you so much for someone (from NHGRI-EBI GWAS Catalog ?) kindly putting the #GWAS pin on our poster at #ASHG24 in Denver😃.
Genetic & phenotypic impact of ancient hunter-gatherer "Jomon" on modern Japanese🧬. Geographical diversity of Jomon genome proportion across Japanese islands🗾🏝️& link with obesity⚖️. Work with Kenichi_Yamamoto_Osk & Shigeki Nakagome using BBJ !! Now Nature Communications ㊗️ nature.com/articles/s4146…
If you are in ACR 2024 at D.C., please join the joint JCR-ACR scientific session (Sat 9:00-10:00am, 145AB), co-moderated with Theresa Lu Lab. 16S07: At the Heart of the Inflamed Vessel: New Insights into Cardiovascular Disease and Vasculitis. #ACR24 #ACRheum
📢Blood DNA virome🧬🦠 assocites autoimmune diseases🔬. Endogeneous human herpesvirus 6B (eHHV-6B) has systemic lupus erythematosus (SLE) risk. Increased anellovirus in SLE, rheumatoid arthritis (RA), COVID-19 Nature Genetics📰#wgs #lupus #virus #covid #gwas nature.com/articles/s4158…
Happy to see our Blood DNA virome🩸🦠project featured as cover art📰🖼️in Nature Genetics. String entangled in wire mesh🧶🗑️represents endogeneous herpes virus integrated in human genome🦠🧬😃. nature.com/ng/volumes/57/…
Human papillomavirus (HPV)🦠integration into human host genome🧬😃drives HPV+ head & neck cancers🦀. Tumor whole-genome seq identified intratumor clonal heterogeneity & genomic instability. Now in Nature Communications🎉 #cancer #genome #virus #HPV #wgs #papilloma nature.com/articles/s4146…
Germline (HLA, CCR6) & somatic mutations (clonal hematopoiesis, mCA)🧬have neuromyelitis optica spectrum disorder risk!! Projecting 21q loss mCA to scRNA-seq showed CD4T-specific somatic cells with type I interferon dysregulation Cell Genomics cell.com/cell-genomics/… #NMOSD #gwas
Germline ＆ somatic mutations at MHC & IGH define COVID-19 vaccine immunogenicity. mCA at 6p-MHC, 14q-IGH, mosaic loss of sex chromosome decrease vaccine titer but increase infection, allergy, rheumatic disease risk. Kyuto Sonehara 南宮湖(Ho Namkoong) Cell Genomics cell.com/cell-genomics/…
Our paper on germline/somatic mutations influencing COVID-19 vaccine immunogenicity is out Cell Genomics! cell.com/cell-genomics/…
Pathway-stratified polygenicity🧬and single cell, metabolome, proteome projection revealed East Asian-specific negative genetic correlation between respiratory🫁& cardiometbolic🫀diseases (e.g. asthma/COPD↔️diabetes). Nature Communications #GWAS #PRS #PGS #proteome nature.com/articles/s4146…
Japan Omics Browser (JOB) japan-omics.jp by Yugo Takahashi & Qingbo Seiha Wang is published #BMCGenomics㊗️. Integrative visualization🎦of Japanese molecular QTL databases🧬💾. bmcgenomics.biomedcentral.com/articles/10.11… #QTL #pQTL #eQTL #GWAS
Please check our platform talk at #ESHG2025🎉 "Multi-layered single-cell genomics deconvolutes biological mechanisms underlying clonal hematopoiesis and mitochondrial heteroplasmy in infectious & autoimmune diseases"🧬🩸by Go Sato & Ryuya Edahiro Session C22.03, Sunday 25 May
