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On the role of extracellular vesicles in malignant transformation in the bladder: nature.com/articles/s4138… #OpenAccess #BladderCancer

Read about the role KPNA2/YBX1 axis in #Osteosarcoma in our latest issue! 🔬nature.com/articles/s4138… #AlternativeSplicing

Could a new microprotein encoded by #lncRNA play a role in #BreastCancer bone metastasis? Find out here: nature.com/articles/s4138…

A new regulatory role of LATS1/2 in modulating immune responses and immune evasion in #OvarianCancer. nature.com/articles/s4138…

Did you know that #ExtracellularVesicles play an important role in #NasopharyngealCarcinoma? nature.com/articles/s4138…

Novel insights into the mechanism by which DNMT1 inhibitors reverse PARPi #resistance. nature.com/articles/s4138…

A new study from Rhys Morgan Sussex Blood Cancer Research shows potential post-transcriptional roles for beta-catenin in myeloid #leukaemia cells. Beta-catenin interacts with a Wnt signalling mRNA network through canonical RNA-binding proteins (RBP) like MSI2. nature.com/articles/s4138…

Exciting new insights into DNA damage repair! 🧬 Researchers uncover how USP10 stabilizes PARP1, forming a positive feedback loop that enhances repair mechanisms. Read more > nature.com/articles/s4138…

Recent findings by Goping lab at UAlberta Med & Dent reveal that unphosphorylated BAD plays a significant role in impeding breast cancer progression and metastasis by activating multiple anti-tumor pathways. Read more >>>> nature.com/articles/s4138…

Recent findings reveal that functional mitochondrial respiration, facilitated by astrocyte-derived mitochondria, is crucial for glioblastoma growth in vivo, supporting coenzyme Q redox cycling and de novo pyrimidine biosynthesis. Read now: nature.com/articles/s4138…

New study shows that downregulating PAR1 enhances the effectiveness of Erastin in treating HPV-negative HNSCC by regulating key ferroptosis-related genes and inhibiting the STAT3 pathway. Read more 🔗 nature.com/articles/s4138…

A newly published article shows that Derlin-3 shapes the tumor microenvironment by modulating ER stress and immune function in #lung cancer and may be promising immunotherapeutic target. Read more 🔗 nature.com/articles/s4138…

A new study shows USP32 is crucial for glycolytic reprogramming and chemoresistance in #PDAC. Its activity depends on CDK5-mediated phosphorylation and combining CDK5 inhibitors with gemcitabine offers a promising anticancer strategy. 🔗 nature.com/articles/s4138…

New research indicates that loss-of-function mutations in the KCNQ1 potassium channel disrupt Wnt/β-catenin signaling in #epithelial cancers, highlighting the critical role of ion channels in regulating cellular pathways and tissue homeostasis. 🔗 nature.com/articles/s4138…

New research reveals that WNT2, upregulated by m6A modification, promotes M2-like macrophage polarization and the malignant progression of nasopharyngeal carcinoma (NPC). Find more about it by reading > nature.com/articles/s4138…

A recent investigation by researchers at Xinxiang Medical University reveals that SIRT2-mediated deacetylation of P5CS is a #critical mechanism by which cancer cells sustain mitochondrial respiration, thereby facilitating the progression of HCC. nature.com/articles/s4138…

New study by BC Cancer researchers identifies integrin-linked kinase (ILK) as a key driver of EMT-mediated resistance to EGFR-TKI therapy in lung #cancer. Targeting ILK, limits drug-tolerant persister cell viability. Read more 🔗 nature.com/articles/s4138…

News from Amelio Lab: Advanced #SalivaryCancer and developing glands share common #p53 pathway regulation. Pro-tumorigenic FGFR2 distinguishes foetal development from high-grade MEC. nature.com/articles/s4138…

LOXL2 as a druggable epigenetic target to overcome PARPi resistance in homologous recombination-deficient models of multiple tumour types. nature.com/articles/s4138…

Scientists may have unlocked the final frontier in medicine: PAUSING cell death. New research by @carinacarlakern et al - with contributions from NASA, @ESA, @Mayo Clinic, and Harvard University — shows necrosis isn’t just the end of a cell. nature.com/articles/s4138…