This is pretty wild. How many other canonical biological processes can be "reversed"?

This is what one year of PhD thesis work looks like. All hail the Tapeball.

This is so good!

one of my favorites is the paper that just put in a capital T for error bars

The final version of our paper on anti-CRISPRs "in disguise" as Cas proteins is out today in Nature! Congrats to Mark, Edith and the whole team! nature.com/articles/s4158…

Doing good science is 90% finding a science buddy to constantly talk to about the project.

BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”

Bulky pastas—like farfalle and fusilli—require more packaging than thinner varieties, making them trickier to transport and leading to more waste. 🍝 On #NationalPastaDay, learn more about a different twist on pasta dough that could help reshape food manufacturing, according to

New review on the 'microbial dark matter' that is Patescibacteria pnas.org/doi/10.1073/pn…

The enigmatic, ultrasmall and largely uncultivated Candidate Phyla Radiation bacteria represent a treasure trove of potential discoveries, argues this recent Perspective in PNAS🕵️👇 from the Mougous Lab University of Washington pnas.org/doi/10.1073/pn…

🎯 Do you really understand p-values? The p-value histogram can reveal a LOT about your data. Let's break it down using real examples.👇

Biology papers be like "The nucleus is part of the cell and contains a lot of DNA. Polycomb Repressive Complex 2 (PRC2)-mediated deposition of H3K27me3 establishes domains of facultative heterochromatin, silencing gene expression in a developmentally regulated manner."

Pseudomonads coordinate innate defense against viruses and bacteria with a single regulatory system biorxiv.org/content/10.110… #biorxiv_micrbio

We are delighted to welcome Joseph Mougous to the Microbial Sciences Institute. An international leader in microbiology and HHMI Investigator, Mougous joins the faculty YaleMicroPath later this year. medicine.yale.edu/news-article/j…

Twists, turns and jumps: T6SS evolution within species dlvr.it/TJTwgC

Recognition of unique cell surface glycopolymers by diversified lectin domains specifies umbrella toxin targeting biorxiv.org/content/10.110… #biorxiv_micrbio

BetaH proteolysis unleashes an electrostatic-homing antibacterial polymorphic toxin biorxiv.org/content/10.110… #biorxiv_micrbio

who needs Adobe Illustrator when MS Paint still exists?

Pseudomonads on GAURD Mougous YaleMicroPath describe immune strategy in Pseudomonas, termed GUARD, that protects against bacteria & viruses. Controlled by Gac/Rsm regulatory pathway, program activates suite of defense mechanisms to general danger signal cell.com/cell-host-micr…