Pablo Munoz Schuffenegger (@pablomunozsch) 's Twitter Profile
Pablo Munoz Schuffenegger

@pablomunozsch

MD. Radiation Oncologist. GI+Thoracic+Oligomets. Associate Professor @FacMedicinaUC @ucatolica 🇨🇱 . Tweets are my own

ID: 394426859

linkhttp://redsalud.uc.cl/ucchristus/Directorio/pablo_munoz_schuffenegger.act calendar_today20-10-2011 01:55:42

3,3K Tweet

1,1K Followers

1,1K Following

Jeff Ryckman (@jryckman3) 's Twitter Profile Photo

🧵1/ Big news in unresectable stage III NSCLC. The InTRist study is the first randomized trial comparing NAC vs. neoadjuvant chemoimmunotherapy (NAC-ICI) prior to definitive chemoradiotherapy (CRT). Early results are promising. Let’s dig in. 🔍 #LungCancer #RadOnc #ASCO25

🧵1/
 Big news in unresectable stage III NSCLC.

The InTRist study is the first randomized trial comparing NAC vs. neoadjuvant chemoimmunotherapy (NAC-ICI) prior to definitive chemoradiotherapy (CRT).

Early results are promising. Let’s dig in. 🔍

#LungCancer #RadOnc #ASCO25
Krishan Jethwa (@krishanjethwa) 's Twitter Profile Photo

🚨CM-577, long term🚨 Resected E/GEJ cancer s/p neoadjuvant CRT + surgery; path residual disease: 🔍Randomized: 12 m nivolumab vs. Surveillance Nivo demonstrated: ✅⬆️DFS ✅⬆️DMFS ✅⬆️OS 🔥PDL1>1 and Esophagus location > benefit 🧐Don’t be fooled be p=0.1 for OS. Study

🚨CM-577, long term🚨

Resected E/GEJ cancer s/p neoadjuvant CRT + surgery; path residual disease:

🔍Randomized: 
12 m nivolumab 
vs. 
Surveillance

Nivo demonstrated: 
✅⬆️DFS
✅⬆️DMFS
✅⬆️OS
🔥PDL1>1 and Esophagus location > benefit

🧐Don’t be fooled be p=0.1 for OS. Study
Krishan Jethwa (@krishanjethwa) 's Twitter Profile Photo

🔥❓Is Pre-op Chemoradiation the new SoC for locally advanced gallbladder cancer❓🔥 🚨POLCA-GB🚨 T3-4 or N+ GB cancer 🔍Gem-Cis +- CRT CRT Demonstrated: ✅⬆️OS, at median and with substantial separation at tail of curve (read: dcurability) ✅⬆️PFS ✅⬆️Objective response ✅No

🔥❓Is Pre-op Chemoradiation the new SoC for locally advanced gallbladder cancer❓🔥

🚨POLCA-GB🚨
T3-4 or N+ GB cancer
🔍Gem-Cis +- CRT

CRT Demonstrated:
✅⬆️OS, at median and with substantial separation at tail of curve (read: dcurability)
✅⬆️PFS
✅⬆️Objective response
✅No
TMC Radiation Oncology (@radonctmc) 's Twitter Profile Photo

Honored to share highlights of Reena Engineer’s presentation of POLCAGB phase III trial at #ASCO2025, a game changer for locally advanced gallbladder cancer Neoadj CRT vs CT alone: 🌟 Nearly doubled mOS (21.8 vs 10.1 months) 🌟 Significantly improved R0 resection (51.6% vs 29.7%)

Honored to share highlights of <a href="/ReenaEngineer/">Reena Engineer</a>’s presentation of POLCAGB phase III trial at #ASCO2025, a game changer for locally advanced gallbladder cancer
Neoadj CRT vs CT alone:
🌟 Nearly doubled mOS (21.8 vs 10.1 months)
🌟 Significantly improved R0 resection (51.6% vs 29.7%)
Dr. Fabio Moraes (@fabiomoraesmd) 's Twitter Profile Photo

All You Need to Know: ASCO 🤝 Google Gemini 🧵 A quick breakdown of this bold move to bring AI into evidence-based oncology care — and what it means for the future. Let’s go: #AI #ASCO25 #DigitalHealth ASCO The ASCO Post Google Julie Gralow gilberto lopes Sandip Patel MD FASCO

All You Need to Know: ASCO 🤝 Google Gemini

🧵 A quick breakdown of this bold move to bring AI into evidence-based oncology care — and what it means for the future. Let’s go:
#AI #ASCO25 #DigitalHealth
<a href="/ASCO/">ASCO</a> <a href="/ASCOPost/">The ASCO Post</a> <a href="/Google/">Google</a> <a href="/jrgralow/">Julie Gralow</a> <a href="/GlopesMd/">gilberto lopes</a> <a href="/PatelOncology/">Sandip Patel MD FASCO</a>
NEJM (@nejm) 's Twitter Profile Photo

Presented at #ASCO25: A 3-year structured exercise program after adjuvant chemotherapy for colon cancer improved disease-free and overall survival, physical functioning, and fitness, as compared with health education alone. Full CHALLENGE phase 3 trial results:

Presented at #ASCO25: 

A 3-year structured exercise program after adjuvant chemotherapy for colon cancer improved disease-free and overall survival, physical functioning, and fitness, as compared with health education alone. Full CHALLENGE phase 3 trial results:
Angela Lamarca (@drangelalamarca) 's Twitter Profile Photo

#POLCAGB trial in locally advanced #GallbladderCancer at #ASCO25 Neoadjuvant CisGem +/- ChemoRad 📊OS and ORR improved 🔪84-77% R0/1 👀Higher postoperative complications 🚨Small sample size Changes my practice? Maybe…. In an “adapted” format 🤔 ASCO SEOM Grupo Español de Tratamiento de Tumores Digestivos

#POLCAGB trial in locally advanced #GallbladderCancer at #ASCO25

Neoadjuvant CisGem +/- ChemoRad

📊OS and ORR improved
🔪84-77% R0/1
👀Higher postoperative complications 
🚨Small sample size

Changes my practice? Maybe…. In an “adapted” format 🤔

<a href="/ASCO/">ASCO</a> <a href="/_SEOM/">SEOM</a> <a href="/GrupoTTD/">Grupo Español de Tratamiento de Tumores Digestivos</a>
Dr. Nina Niu Sanford (@niusanford) 's Twitter Profile Photo

Just brand it “Exercizumab!” 😃 In all seriousness, I have been recommending exercise during & after treatment to all my patients who are able to. Great to have Level 1 evidence supporting this strategy. Now need systematic change to upscale & implement. #ASCO25

Shankar Siva (@_shankarsiva) 's Twitter Profile Photo

Drew Moghanaki “possibility VALOR phIII RCT of surgery vs SABR will show no difference in stage I #lungcancer” #radonc #SABR2025 🇨🇦 🟰several studies showing no diff ⬇️ trends for surgery in 🇺🇸 🤔 sampling LNs in solid dom GGO not needed ⚖️ ?benefit of lobectomy nasser altorki

<a href="/DrewMoghanaki/">Drew Moghanaki</a> “possibility VALOR phIII RCT of surgery vs SABR will show no  difference in stage I #lungcancer” #radonc #SABR2025 🇨🇦
🟰several studies showing no diff
⬇️ trends for surgery in 🇺🇸
🤔 sampling LNs in solid dom GGO not needed 
⚖️ ?benefit of lobectomy <a href="/AltorkiNasser/">nasser altorki</a>
Gerry Hanna (@gerryhanna) 's Twitter Profile Photo

In this month's Radiotherapy & Oncology Van Aken, et al describe a framework to assess interactions and safety of targeted therapes or #Immunotherapy combinations with #Radiotherapy ➡️Pragmatic and biologically informed guidance on how to address 🔗doi.org/10.1016/j.rado…

In this month's <a href="/RO_GreenJournal/">Radiotherapy & Oncology</a> Van Aken, et al describe a framework to assess interactions and safety of targeted therapes or #Immunotherapy combinations with #Radiotherapy 

➡️Pragmatic and biologically informed guidance on how to address

🔗doi.org/10.1016/j.rado…
Universidad Católica (@ucatolica) 's Twitter Profile Photo

#RankingQS 🥇| 1ra en Chile y top 3 de Latinoamérica. Un nuevo QS World University Rankings reveló que la #UC sigue liderando las ues. del país y destaca entre las 200 mejores del mundo en cuatro indicadores. 🌎Además, alcanzó el lugar 36º en Reputación Académica. acortar.link/MlMVOs

#RankingQS 🥇| 1ra en Chile y top 3 de Latinoamérica. Un nuevo <a href="/worlduniranking/">QS World University Rankings</a> reveló que la #UC sigue liderando las ues. del país y destaca entre las 200 mejores del mundo en cuatro indicadores. 🌎Además, alcanzó el lugar 36º en Reputación Académica. acortar.link/MlMVOs
Jonas Willmann, MD (@jonas_willmann) 's Twitter Profile Photo

❓ESTRO & EORTC proposed a classification to standardize reirradiation. But does it predict outcomes or toxicity? 🫁☢️ We applied the classification in thoracic reirradiation for NSCLC. Here’s what we found. 🧵

IASLC (@iaslc) 's Twitter Profile Photo

🌍 How is lung cancer managed around the world? Join us July 3 for a global tumor board tackling real case discussions from diagnosis to survivorship. Featuring experts: Rajat Thawani, Ilit Turgeman, Pramesh CS, Roselle De Guzman, Pablo Munoz Schuffenegger & more! 🔗 bit.ly/43WgnFa

🌍 How is lung cancer managed around the world?
Join us July 3 for a global tumor board tackling real case discussions from diagnosis to survivorship.

Featuring experts: <a href="/rajatthawani/">Rajat Thawani</a>, <a href="/TurgemanIlit/">Ilit Turgeman</a>, <a href="/cspramesh/">Pramesh CS</a>, <a href="/DrRoselleDG/">Roselle De Guzman</a>, <a href="/pablomunozsch/">Pablo Munoz Schuffenegger</a> &amp; more! 
🔗 bit.ly/43WgnFa
Dr. Nina Niu Sanford (@niusanford) 's Twitter Profile Photo

Thank you so much, Simul Parikh, for this excellent blog post on NRG GI-011, which explains our study rationale & logistics perfectly. We hope our trial is of interest to academic practices, community sites, & everything in between V grateful for your support🙏 Full link below

Thank you so much, Simul Parikh, for this excellent blog post on NRG GI-011, which explains our study rationale &amp; logistics perfectly.

We hope our trial is of interest to academic practices, community sites, &amp; everything in between

V grateful for your support🙏

Full link below
Angela Lamarca (@drangelalamarca) 's Twitter Profile Photo

Numbers that I am still digesting from todayat @myesmo #ESMOGI25 come from the #KeynoteLecture by #ElisabeteWeiderpass Take home message 1/3 🧵 🌍 Burden of type of GI cancer varies accross countries #ESMOAmbassadors

Numbers that I am still digesting from todayat @myesmo #ESMOGI25 come from the #KeynoteLecture by #ElisabeteWeiderpass

Take home message 1/3 🧵
🌍 Burden of type of GI cancer varies accross countries

#ESMOAmbassadors
OncoDaily (@oncodaily) 's Twitter Profile Photo

Tennis and the Physician-Scientist - Lessons from the Court to the Clinic and Lab - Dr. Fabio Moraes oncodaily.com/blog/324126 #OncoDaily #Oncology #Cancer #Health #Medicine #MedX

Tennis and the Physician-Scientist - Lessons from the Court to the Clinic and Lab - <a href="/fabiomoraesmd/">Dr. Fabio Moraes</a> 

oncodaily.com/blog/324126

#OncoDaily #Oncology #Cancer #Health #Medicine #MedX
Cancer Research @UCC (@canresucc) 's Twitter Profile Photo

Could tumour growth speed predict outcomes in oligoprogressive cancer treated with SBRT? In a study of Stereotactic Body Radiotherapy treated patients Aisling Barry & team find tumour-specific growth rate may help identify who benefits most from treatment, irrespective of type.

Could tumour growth speed predict outcomes in oligoprogressive cancer treated with SBRT?
In a study of Stereotactic Body Radiotherapy treated patients <a href="/aislingbarryro/">Aisling Barry</a> &amp; team find tumour-specific growth rate may help identify who benefits most from treatment, irrespective of type.
Pablo Munoz Schuffenegger (@pablomunozsch) 's Twitter Profile Photo

Excelente review Kimmie Ng, MD, MPH Dana-Farber sobre cáncer gastrointestinal de inicio temprano. Un desafío creciente a nivel global que requiere prioridad para investigación y prevención 👇👇