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A day full of DA neurons subtypes discussions in our in person retreat in LaJolla, CA. Our trainees did an excellent job with their presentations! The venue by the ocean was definitely a plus. ASAP Team Awatramani Aligning Science Across Parkinson’s BevanLab @DanielDombeck raj awatramani

The honor was mine to visit an excellent Department that does a fantastic job in Parkinson's disease research at multiple (basic, translational) levels. VAI Department of Neurodegenerative Science #LRRK2 #Parkinsons

The inspirational documentary “Still” about Michael J. Fox opened the Doc10 Film Festival in Chicago. Highlight the Q&A session with director Davis Guggenheim. Strong representation of ASAP Team Awatramani team members.

A LRRK2 focused day resulted in new collaborations in beautiful Brussels with (some!!) Belgian beer. Wim Versees was an excellent host. Highlight: I got to see Elisa Greggio in person after almost 13 years. Aligning Science Across Parkinson’s ASAP Team Awatramani

A must-read article! Heterogeneity in the dopamine neurons subtypes of the substantia nigra reevaluated through a collaborative effort! Congrats to @DanielDombeck and raj awatramani! Aligning Science Across Parkinson’s OpenSci Talk @collaboration

Dopamine And Parkinson’s: Challenging Over 100 Years Of Research radiohealthjournal.org/dopamine-and-p…

Hurray! 🎉🎉🎉 So excited about this!!! More excited to do this with Elisa Greggio

I am excited this is now published with eLife - the journal. LRRK2/actin cytoskeleton/synapses is a favorite recurring theme of mine 😊. A fun collaboration with Elisa Greggio "LRRK2 regulates synaptic function through BDNF signaling and actin cytoskeleton" doi.org/10.7554/eLife.…

I am thrilled to present at this meeting, which brings together two of my favorite things in life- #LRRK2 and @Greek Islands. Register now to learn about the latest discoveries on #LRRK2 and explore the stunning island of Crete.

Check out our new preprint live on BioRxiv looking at molecular and spatial mapping of #dopamine neurons in a LRRK2 model of Parkinson's Disease! raj awatramani ASAP Team Awatramani biorxiv.org/content/10.110…

🎉I am thrilled to be part of this. It shows 1) a refined classification of midbrain dopamine neurons 2) single nucleus RNA sequencing changes in synaptic pathways of LRRK2 dopamine neuron subclusters A collaborative effort of ASAP Team Awatramani @DanielDombeck raj awatramani

Pathogenic LRRK2 causes age-dependent and region-specific deficits in ciliation, innervation and viability of cholinergic neurons biorxiv.org/content/10.110… LRRK2 knock-in mice can be a valuable early disease model for PD. Notable age-dependent and cell type-specific LRRK2 effects!

That is by all means my favorite email text...😊🥳 "A notice of award has been received for the referenced funding proposal. The Notice of Award has been uploaded into the Grants system and is currently being reviewed."

The finalized version of our latest paper is live in eLife - the journal! Molecular and spatial transcriptomic classification of midbrain dopamine neurons and their alterations in a LRRK2G2019S model of Parkinson’s disease doi.org/10.7554/eLife.…

🎉🎉 🎊🎊Our latest research has just been published in Molecular Psychiatry Springer Nature. We showed that increased kinase activity of Parkinson’s disease LRRK2 underlies the motoric side effects of antipsychotics. nature.com/articles/s4138…

🎊🎊 The Feinberg School of Medicine News Center has just feature our latest research Northwestern Basic Sciences ! news.feinberg.northwestern.edu/2025/04/30/ide…

A new study led by the Parisiadou lab (Loukia Parisiadou) uncovers the molecular mechanisms behind why a commonly prescribed antipsychotic drug can cause harmful side effects resembling #ParkinsonsDisease symptoms, per findings in Molecular Psychiatry. tinyurl.com/y7jc5f9n

New data from Zachary Gaertner raj awatramani & collaborators provides molecular & spatial transcriptomic classification of midbrain dopamine neurons & their alterations in a LRRK2G2019S model of #Parkinsons; 20 distinct DA neuron subtypes in 3 main families elifesciences.org/articles/101035

Northwestern Medicine investigators have identified the molecular mechanisms that cause a commonly prescribed #antipsychotic drug to produce harmful side effects similar to #ParkinsonsDisease symptoms, molecularpsychiatry. spr.ly/6015N2Iv7

Reviewing NIH grants, I totally enjoy the simplified review scoring criteria. Is this research worth doing (significance)? If so, can it be done well (approach)? These two core aspects are what truly matter.