Paul Chen (@paulchenz) 's Twitter Profile
Paul Chen

@paulchenz

Postdoc @liugroup & Langer Lab | 2022 @SchmidtFellows | interested in genome editing, materials design and accelerating discovery

ID: 4765523742

calendar_today16-01-2016 00:56:13

913 Tweet

795 Followers

319 Following

David R. Liu (@davidrliu) 's Twitter Profile Photo

Sammy Basso Sammy Basso, one of the most remarkable people to share our world, passed away last night from complications associated with progeria, the ultra-rare ‘rapid aging’ genetic disease Sammy both suffered from and transcended. Sammy realized that a base editing treatment

Sammy Basso <a href="/SammyBasso/">Sammy Basso</a>, one of the most remarkable people to share our world, passed away last night from complications associated with progeria, the ultra-rare ‘rapid aging’ genetic disease Sammy both suffered from and transcended. 

Sammy realized that a base editing treatment
Nicole M. Gaudelli (@nicolegaudelli) 's Twitter Profile Photo

Congratulations to David R. Liu for being awarded the 2024 A.I. Scott medal in Chemistry. It was also the first time all four of us presented at the same event! Komor Lab

Congratulations to <a href="/davidrliu/">David R. Liu</a> for being awarded the 2024 A.I. Scott medal in Chemistry.  It was also the first time all four of us presented at the same event!  <a href="/KomorLab/">Komor Lab</a>
David R. Liu (@davidrliu) 's Twitter Profile Photo

Today we report in Nature Biotechnology a system for the laboratory evolution of engineered virus-like particles (eVLPs) that enables the discovery of eVLP variants with desired properties, including improved production and delivery potency. 1/13 PDF: drive.google.com/file/d/1E6Nr86…

Today we report in <a href="/NatureBiotech/">Nature Biotechnology</a> a system for the laboratory evolution of engineered virus-like particles (eVLPs) that enables the discovery of eVLP variants with desired properties, including improved production and delivery potency. 1/13
PDF: drive.google.com/file/d/1E6Nr86…
Aditya Raguram (@adityaraguram) 's Twitter Profile Photo

Excited to share our new system for evolving eVLPs with improved production and protein delivery efficiencies! Grateful to David R. Liu and liugroup for support throughout this study, and special thanks to co-authors Meirui An and Paul Chen for their contributions!

John Evans (@john_evans3) 's Twitter Profile Photo

Privileged to share initial data for BEAM-302 today in alpha-1 antitrypsin deficiency (AATD)! AATD is a severe, progressive disease impacting both lung and liver function that affects 100,000 people in the US globenewswire.com/news-release/2…

Breakthrough (@brkthroughprize) 's Twitter Profile Photo

David Liu wins the Breakthrough Prize in Life Sciences for developing gene-editing technologies, including a "molecular word processor" that can find and replace whole sequences of DNA. His tools are already impacting diseases including cancer. breakthroughprize.org/News/91

David Liu wins the Breakthrough Prize in Life Sciences for developing gene-editing technologies, including a "molecular word processor" that can find and replace whole sequences of DNA. His tools are already impacting diseases including cancer. breakthroughprize.org/News/91
Broad Institute (@broadinstitute) 's Twitter Profile Photo

David Liu receives Breakthrough Prize in Life Sciences. David R. Liu is honored for the development of base editing and prime editing, two gene editing technologies transforming medicine. Breakthrough broadinstitute.org/news/david-liu…

David Liu receives Breakthrough Prize in Life Sciences.
<a href="/davidrliu/">David R. Liu</a> is honored for the development of base editing and prime editing, two gene editing technologies transforming medicine. <a href="/brkthroughprize/">Breakthrough</a> broadinstitute.org/news/david-liu…
David R. Liu (@davidrliu) 's Twitter Profile Photo

Last night I was honored to receive the 2025 #BreakthroughPrize in the Life Sciences, reflecting the efforts of many students, collaborators, doctors, and patients in labs around the world. I hope this 4-minute excerpt can inspire when science needs public support more than ever.

Children's Hospital (@childrensphila) 's Twitter Profile Photo

CHOP & Penn Medicine have delivered the first-ever personalized gene editing therapy for a patient with CPS1 deficiency, marking a major milestone in the application of CRISPR-based treatments. Learn more about KJ & the future of personalized medicine: ms.spr.ly/6015SZLAx.

David R. Liu (@davidrliu) 's Twitter Profile Photo

In a medical milestone, a customized base editor was developed, characterized in human and mouse cells, tested in mice, studied for safety in non-human primates, cleared by U.S. FDA for clinical trial use, manufactured as a complex with an LNP, and dosed into a baby with a severe,

In a medical milestone, a customized base editor was developed, characterized in human and mouse cells, tested in mice, studied for safety in non-human primates, cleared by <a href="/US_FDA/">U.S. FDA</a> for clinical trial use, manufactured as a complex with an LNP, and dosed into a baby with a severe,
David R. Liu (@davidrliu) 's Twitter Profile Photo

Today in Science Magazine we report the development of a laboratory-evolved CRISPR-associated transposase (evoCAST) that supports therapeutically relevant levels of RNA-programmable gene insertion in human cells, a collaboration with Sternberg Lab. 1/13 drive.google.com/file/d/1I-UbCR…

Today in <a href="/ScienceMagazine/">Science Magazine</a> we report the development of a laboratory-evolved CRISPR-associated transposase (evoCAST) that supports therapeutically relevant levels of RNA-programmable gene insertion in human cells, a collaboration with <a href="/SternbergLab/">Sternberg Lab</a>.
1/13
drive.google.com/file/d/1I-UbCR…
HHMI (@hhminews) 's Twitter Profile Photo

A baby named KJ, who was born with a rare genetic disorder – CPS1 deficiency – is healed thanks to doctors at the Children's Hospital who administered the world’s first personalized gene-editing treatment. The research team used base editing, a gene-editing method invented by HHMI

A baby named KJ, who was born with a rare genetic disorder – CPS1 deficiency – is healed thanks to doctors at the <a href="/ChildrensPhila/">Children's Hospital</a> who administered the world’s first personalized gene-editing treatment. The research team used base editing, a gene-editing method invented by HHMI
Alice Stanton (@alicestanton) 's Twitter Profile Photo

Absolutely thrilled to make public that I am joining the Harvard Medical School Harvard Medical School and MGB CGM at MGH Center for Genomic Medicine and MGH Neurology Department of Neurology as an Assistant Professor: stantonlab.info. 🧵

Sternberg Lab (@sternberglab) 's Twitter Profile Photo

1/10 Today in Science Magazine in collaboration with liugroup we report the development of a laboratory-evolved CRISPR-associated transposase (evoCAST) that supports therapeutically relevant levels of RNA-programmable gene insertion in human cells. drive.google.com/file/d/1I-UbCR…

1/10 Today in <a href="/ScienceMagazine/">Science Magazine</a> in collaboration with <a href="/liugroup/">liugroup</a> we report the development of a laboratory-evolved CRISPR-associated transposase (evoCAST) that supports therapeutically relevant levels of RNA-programmable gene insertion in human cells. drive.google.com/file/d/1I-UbCR…
David R. Liu (@davidrliu) 's Twitter Profile Photo

Another medical milestone! The first patient treated with a prime edited therapeutic shows positive clinical outcomes consistent with effective rescue of his chronic granulomatous disease (CGD), a debilitating and life-shortening primary immunodeficiency. At least 19 base editing

Another medical milestone! The first patient treated with a prime edited therapeutic shows positive clinical outcomes consistent with effective rescue of his chronic granulomatous disease (CGD), a debilitating and life-shortening primary immunodeficiency.
At least 19 base editing
David R. Liu (@davidrliu) 's Twitter Profile Photo

I discuss the urgent crisis from the loss of federal support of science in the US and recent clinical gene editing breakthroughs with Walter Isaacson & Christiane Amanpour on Amanpour and Company, airing on PBS tonight at 11 pm ET, and on CNN International earlier today. Pls share! youtube.com/watch?v=8YhJM6…