1/ Just out in Nature Medicine : we show the opioid system modulates ketamine’s effects in major depressive disorder, with naltrexone pre‑treatment reducing acute glutamatergic activity and acute antidepressant effects. nature.com/articles/s4159…

“Nervously, Mario approached the Vatican gates. ‘I rang the bell and said, “Good morning, I'm the Pope's barber. Who called you?” they asked. “The Pope,” I said. “The Pope called you? One moment, please.” A moment later, a staffer came out holding a notice confirming the Pope's

I’m a cardiologist. Here are 10 science-based ways to prevent heart disease. washingtonpost.com/wellness/2025/…

I could not help but think Through the thunder rolling stink That I was just a puppet in a play And through the roar and smoke The string is finally broke And a cannonball blew my eyes away — Bob Dylan — John Brown October 15, 1987 London, England.

I just wanted to thank you for starting cost plus drugs. My husband was diagnosed with a rare autoimmune disease, Neuromyeltis Optica (NMO). Recently he had some other symptoms and was prescribed Ampyra . Our insurance company denied his claim so I called XXXX and was informed

1/ AI-Associated Psychosis is increasingly reported in the media and in online spaces like Reddit. I've seen cases in clinical practice and have received emails from concerned friends/family about loved ones falling down the rabbit hole. Here's some explanations/tips to help...

This reminds me of the story about Freud needing to sign a statement that he hadn’t been mistreated by the gestapo in order to leave Austria. He reportedly asked to add a statement and with their permission wrote “The Gestapo were wonderful. I would recommend them to all my

“Madness in great ones must not unwatch’d go” Hamlet Act 3 Scene 1

Kharkiv right now ❤️‍🩹 I’m almost crying. We’re banned from organizing celebrations. Warned against crowds and gatherings due to constant russian bombings. But we’re alive, and we’ll keep living. That’s our collective "fuck you" to russia.

Finally. Thank you 🙏🏼 open.substack.com/pub/peterstone…

Constituent: I am pissed, and I am pissed at you. The man is a dictator. He knows nothing about what he talks about. You need to take your head out of Trump’s ass.

Abbe Lowell and I represent CDC Director Susan Monarez. Contrary to govt statements, Dr. Monarez has neither resigned nor yet been fired. We have issued the following statement:

We are in uncharted and dangerous territory in regard to our public health and scientific capacity. As a physician who has cared for patients nearly half a century I know how hard making medical decisions is and getting clinical care right. If one is not humbled by this they

💫 Join me ONLINE this Monday evening for a special Dharma talk and Meditation, 6:30-8:30pm PT, presented by Spirit Rock. Learn more & register: go.spiritrock.org/4p7eDBm

Paul Summergrad, M.D. Thanks for pointing it out - I realized this too late but you are absolutely correct, I mistakenly thought this was a position statement and it is NOT😭