🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Current position: The Desert of This-Is-Never-Gonna-Be-Over-And-I'm-Going-To-Die-Here (but with a paper in review IRL) If you need to chart your course you can order a poster here - on sale now! redbubble.com/people/redpenb…

Plant a forest with us and Treedom! To celebrate #Earthday2023, we are working with Treedom to add 500 trees in our already existing European Space Agency forest. But you can help us plant more: we are going to add one tree for each like to this article: esa.int/Applications/O…

NOW OUT Science Magazine 🧬🐾🤓 “The evolution of two transmissible cancers in Tasmanian devils” A 🧵 on our deep DNA sequencing dive into the startling genetic history of contagious tumours (1/n) 👇 doi.org/10.1126/scienc…

When they said Excel is really powerful if you know how to use it: pub.towardsai.net/building-a-neu…

Read this. Worth 5 minutes of your time. It matters who does science science.org/content/blog-p…

Some species are extremely resistant to cancer, would you like discover the molecular and cellular mechanisms responsible? My lab and the @odom_lab have a computational postdoc position open: jobs.dkfz.de/en/jobs/145480…

Very proud to introduce you SComatic (Nature Biotechnology ): a breakthrough method for detecting somatic mutations in single-cell datasets without using a reference sample. Amazing work carried out with the huge support of Isidro Cortes-Ciriano and all co-authors! EMBL-EBI EMBL

Since I am talking about p-values today (only day this year I promise), the common claim that p-vals are uniform under the null is not in general true. Even in theory. Here is the dist of p-values under null for logistic regression, two groups:

First paper for @AlexBendel_, together with Andre Faure @ajfaure.bsky.social and Ben Lehner. We measured how all mutations in JUN’s leucine zipper perturb it’s interaction with all 54 human bZIPs. biorxiv.org/cgi/content/sh… (1/4)

Big news!! I can finally officially announce that a few weeks ago, ALLOX ALLOX was co-founded by the brilliant André Faure Andre Faure @ajfaure.bsky.social , Pablo Baeza Pablo Baeza Centurion , Ben Lehner Ben Lehner , and myself, who will be stepping in as CEO of the company.

Great opportunity to work with an outstanding team! #sciencejobs #hiring

KRAS is a notorious oncogene, found mutated in 1 in 10 human cancers. A study in nature by researchers at the CRG and Wellcome Sanger Institute reveals the protein's secret vulnerabilities. The work presents the first complete control map for any protein.

⚠️ Research Alert! ⚠️ Research Alert! New paper out in Nature reveals the "kill switches" of a protein misregulated in 10% of cancers! Super cool study led by the one and only Chenchun Weng with the involvement of ALLOX co-founders Andre Faure @ajfaure.bsky.social and Ben Lehner nature.com/articles/s4158…

Come join us as a Research Associate at ALLOX to work on massive scale experiments in probably the best city in the world. pls RT allox.bio/careers

Q: What could GO WRONG with a major cancer genomics study in which tumours are sequenced to only 15x depth? A: An awful LOT! 😟 Our detailed reanalysis now out in Royal Society Publishing: tinyurl.com/RSOSrebuttal 🧵👇 (1/18)

Our team in #Barcelona is expanding & we're #hiring 2 talented scientists to fill these exciting new positions: a Lead Scientist & a Research Associate. Do u want to make a real difference in the future of applied high-throughput genetics and therapeutics? #PhdChat #ScienceJobs

Come and join the extraordinary team of ALLOX and help us accelerate the discovery of more effective therapies! 👉allox.bio/careers

We have two new openings for scientists in our growing team ALLOX ! 📈 Please RT and help us spread the word 🙏🏼

One more week to apply for the Lead Scientist position at ALLOX! 👉 allox.bio/careers/lead-s… At ALLOX, we're systematically mapping all allosteric sites in disease-causing proteins to enable and accelerate the development of novel, safer, and better treatments.

🧪 Are you passionate about molecular cloning? 🧬 Are you interested in applying ingenious methods for generating mutant libraries? 💊 Are you excited to join an exceptional team of scientists committed to revolutionising drug discovery? If so, here is a new job opportunity 👇