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New and exciting work from our lab! ɑ-Synuclein strains influence multiple system atrophy via central and peripheral mechanisms biorxiv.org/content/10.110…

Fascinating work! 👏🏻 wonder what cofactors and PTMs would be needed to replicate MSA seeds?

Highly recommend!

Join us for the synuclein meeting that will be hosted in Leuven next year - call for abstracts open today! synuclein.org/abstracts/

defeatmsa.org/new-request-fo… Joel Watts @Woerman_Lab Michael Henderson Wouter Peelaerts Lynne Krohn @alpha_synuclein Synuclein2019 Patrik Brundin MD PhD

An hour long Question & Answer Session about #MSA Research. Learn the latest from a panel of scientists at the Defeat MSA Alliance conference! Michael Henderson Wouter Peelaerts Ziv Gan-Or #synuclein #Parkinson youtu.be/MSz8V0lm3ec

Two more weeks to submit an abstract for the 2022 synuclein conference in Leuven - synuclein.org/abstracts/ Preliminary program online

Amazing line up of speakers at the Synuclein Meeting 2022 (including @MaluTansey Chandra Lab Wade-Martins Lab Jens Schwamborn Wouter Peelaerts Laura Volpicelli Alberto J Espay Luis M Oliveira Peter Vangheluwe KlenermanLab Anke Van der Perren & more): synuclein.org/preliminary-pr…

New research from Wouter Peelaerts & colleagues reports multiple systems atrophy (MSA) phenotype in mouse models is governed by both the strain of alpha synuclein & the host environment, plus strains can directly trigger a detrimental immune response academic.oup.com/brain/advance-…

Torre Murazabal et al. show that ɑ-synuclein strains determine disease severity in a model of multiple system atrophy via host-restricted and cell-specific pathology. bit.ly/3BAWh3p

Host oligodendrogliopathy and synuclein strains are important determinants of experimental MSA - our latest study in Brain

Synuclein meeting KU Leuven kick off - full house and lots of exciting topics to discuss! #synuclein2022

Ok these guys know beer #synucleinmeeting2022 #Leuven

Infections as triggers of #synucleinopathy? Here is another commentary addressing this interesting notion and focusing on urinary tract infections with JC virus & #MSA. #parkinson ⁦Wouter Peelaerts⁩ ⁦The Science of Parkinson's⁩ ⁦Peter Schmidt⁩ prd-journal.com/article/S1353-…

Could multiple system atrophy be triggered by urinary tract infections? Our latest work - excited to see this out;

Een verhaal dat we vaak hoorden maar nooit echt onderzocht hadden - kunnen blaasontstekingen een trigger zijn van MSA? Ons onderzoek toont aan dat de link sterker is dan we dachten. Van Andel Institute (VAI) Patrik Brundin MD PhD

New paper from Veerle BAEKELANDT et al finds #Parkinsons-associated LRRK2-G2019S variant significantly increases the disease phenotype & inflammatory response in a mouse model of experimental colitis (DSS); Bone marrow transplantation of WT cells rescues this link.springer.com/article/10.100…

I'm such a sucker for reviews on infections in the etiology of #Parkinsons Thank you Wouter Peelaerts & team - this is my weekend reading content.iospress.com/articles/journ…