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One last hurrah in Halifax before we head back to Montreal! Thanks for the great conference Canadian Society for Immunology, we loved our time by the ocean 🌊. The Lachine Canal just isn’t the same 😔 #CSI2022

Last weekend we had a very special event: our first Mandl lab wedding! 😍 Ph.D. student Connie (connie shen) got married in Vermont on the shores of Lake Champlain, and she boldly invited the whole lab to come witness it. Congrats Connie! 🥳

Connie & Jeremy enjoying #celllavie2 sbcf.fr/en/event/cell-… in Paris showing off our newest movies of human neutrophils and T cell crowds.

After they learned what everyone studied, two patrons at this little gay bar in Galveston TX started chanting “Cell migration! Cell migration Surest sign of a successful Gordon Research Conferences 😃

Submitted! Thank you Canadian Society for Immunology for the travel award to attend International Union of Immunological Societies congress in Cape Town! Incredibly excited to visit South Africa and talk immunology with everyone 👩🏻‍🔬

Our aMAZ(E)ing #MidweekMovie comes from connie shen, Mandl Lab, Nienke Vrisekoop and colleagues. They discover that neutrophils with segmented nuclei have a speed advantage when migrating through confinement spaces. 📖J Cell Science: journals.biologists.com/jcs/article/13…

Why do neutrophils have multi-lobed nuclei? 🧐 Does this enable their rapid migration through tight spaces? 🏃‍♀️💨 In this study, we sought to answer this question experimentally 🔬 Here is what we found 👇

Wondering what we can learn from the T cell receptor beta sequence about the self-reactivity of a T cell? check out our paper in Cell Systems where we used machine learning to ask this very question👇: cell.com/cell-systems/f…

10 years after I helped generating an Otub1 knock-out mouse model in the durocherlab, now Dr. Vincent M Luo cracked it down... With the immense help of the Mandl Lab, he identified the γ-Subunit Gng2 as a novel substrate of Otub1 in splenic B cells. tandfonline.com/doi/full/10.10…

Check out our recent publication in collaboration with the Khadra Lab at McGill University - where computational modelling 🖥️ and experimental immunology 🔬join forces to study the role of T cell diversity and antigen binding strength on chronic infection clearance! Find out more 👇

Huge congratulations to Dr. Connie Shen connie shen on delivering an outstanding thesis defense! Our fourth Mandl PhD will soon be leaving the nest, trading cold Montréal for sunny California! ☀️All the best!