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How can you not think about the Roman Empire?

What leads us to ignore experts isn't their knowledge. It's their arrogance. Evidence: Scientists are more credible when they admit what they don't know, acknowledge what they got wrong, and update their views. Trust is earned by expressing humility, not by asserting authority.

⁦Giannicola Genovese MD, PhD⁩ “EMT favours the emergence of genomic-unstable, highly fit tumour cells, which strongly supports the concept of cell-state-restricted patterns of evolution” ⁦MD Anderson Cancer Center⁩ nature.com/articles/s4158…

Out today in ⁦nature⁩ our work on the role of cell plasticity in shaping tumor evolution. Led by ⁦Luigi Perelli⁩ with critical contributions from ⁦Davide Cittaro⁩, Fei Chen and many other outstanding collaborators. 1/2 nature.com/articles/s4158…

Cancer cells leverage epithelial-to-mesenchymal transition (EMT) to promote treatment resistance and metastasis. Results from a recent MD Anderson study found that EMT is a necessary step for pancreatic tumors to become malignant. Learn more: brnw.ch/21wR9Zv #EndCancer

The role of cell plasticity in shaping tumor evolution - Giannicola Genovese (Giannicola Genovese MD, PhD) nature Luigi Perelli Davide Cittaro Ospedale San Raffaele Broad Institute MD Anderson Cancer Center oncodaily.com/blog/252364 #OncoDaily #MedTwitter #MedEd #MedOnc #MedNews #Oncology #Cancer #Health

1/ Out today in Cancer Cell our work on spatial subtypes and cellular neighborhoods of cancer-associated fibroblasts (CAFs)! Led by the brilliant yunhe liu with key contributions from Anirban Maitra Humam Kadara and many collaborators MD Anderson Cancer Center cell.com/cancer-cell/fu…

Stromal mutations occur, but hard to prove they are functional. In our new paper with Trey Ideker’s lab and led by Dr. Mohita Tagore and Maayan Baron, we show that we can find these by looking for mutations across a “class” of genes rather than single genes: nature.com/articles/s4158…

1/5 People living with sickle-cell disease (SCD) face ↑ cancer risk, including #RenalMedullaryCarcinoma. Our latest Immunity study suggests a culprit is the reshaping CD8⁺ T cell chromatin by SCD 👉authors.elsevier.com/sd/article/S10… #MsaouelLab

Evolutionary insights highlight pancreatic cancer target nature.com/articles/d4247…

CPRIT has awarded ~$2B to UT institutions to date to drive cancer breakthroughs. These latest grants go to: The University of Texas at Arlington, UT Austin, UTEP, UTHealth Houston, UT Health San Antonio, MD Anderson Cancer Center, @UTMBHealth, @UTRGV, UT Southwestern Medical Center. Great news and much appreciation #txlege

This is an absolutely shocking piece of data (not surprised, just shocked when you see it visually displayed like this). Prevalence of obesity amongst G7 countries ages 5-19. Red line - 🇺🇸 From the MAHA report focusing on children’s health: whitehouse.gov/wp-content/upl…

🧵1/ T cells have deservedly been in the🔦for #cancer #immunotherapy, but other engineered cell therapies are now📈. What mediates NK cell exhaustion remains an important unanswered❓. 📄Link: nature.com/articles/s4158… I’m so thrilled🥳to share our work out now🚨nature

We are hiring! Apply if you are interested in fundamental questions of cancer biology and applying the state of the art of genetic engineering. linkedin.com/posts/luigi-pe…

What it would take to get America healthier, a new nature feature nature.com/articles/d4158…

🚨 New paper in Nature Genetics ! How does cancer chemotherapy reshape the HSC landscape and drive the evolution of therapy-related myeloid neoplasms? We uncovered this process through single-colony WGS! See the full paper here! nature.com/articles/s4158…

Now that we can assay thousands of plasma proteins in 1-2 ml of blood, there's discovery of many new cancer biomarkers nature.com/articles/s4155…

The newly discovered microbe provisionally known as Sukunaarchaeum isn’t a virus. But like viruses, it seemingly has one purpose: to make more of itself. Learn more: scim.ag/4eGtttN News from Science