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Bioenergetic stress potentiates antimicrobial resistance and persistence | Nature Communications nature.com/articles/s4146…

A much awaited regulatory guidance document! The UK Medicines and Healthcare products Regulatory Agency (MHRA) has announced new guidance for developing #phage therapies in the UK. buff.ly/Ahep5gn

Out Now! Flipping the magic switch to persistence via GTP depletion bit.ly/3TbTNCl #Microbiology #Antibiotics #BacterialPersistence

A bacterial toxin–antitoxin system as a native defence element against RNA phages | Biology Letters royalsocietypublishing.org/doi/full/10.10…

#CharlaCORBI Resistencias Antimicrobianas #RAM y soluciones como #CRISPR #Fagoterapia 📆 26 Junio 19:30h 📍Museo Domus, A Coruña Bruno Gonzalez Zorn Rafa Pinilla-Redondo Os esperamos!!

👩‍🚀 💫Our July issue is now live! Read it here ⬇️ nature.com/nrmicro/volume… Inside: 🛰️Phage satellites 🧬Mobile genetic element interactions and evolution in bacteria 💊Bacterial metabolism and antimicrobial resistance 🎯SARS-CoV-2 spike ...and more!

Mil gracias por la invitación. Fantástico curso 💕

¿Están vivos los virus? Por fin una pista elpais.com/proyecto-tende… vía EL PAÍS

Latest BREX story from the lab - turns out there is a nuclease after all! Congrats to Jenny Readshaw and the whole team, including wonderful collabs Barry Stoddard, Brett Kaiser and Darren Smith. Nucleic Acids Res New England Biolabs Durham BioSciences academic.oup.com/nar/article/53…

Gracias por venir!! #SomosChuac #INIBIC 💕 Bruno Gonzalez Zorn Rafa Pinilla-Redondo #ResistenciasAntimicrobianas

Happy to join the Global Clinical Phage Rounds (G-CPR) for a journal club on the landmark paper discussing 100 consecutive cases in Belgium with #phage therapy (Pirnay et al, Nature Microbiology 2024) with Jean-Paul Pirnay , me, and Sarah Djebara M.D. Today! Scan to sign up.

Phage DNA modifications evade defense: Phage DNA modification adds arabinose to cytosines via hydroxy linkage(5ara-hC) w/potential double & triple arabinosylation. Arabinosylated phages are protected from DNA-targeting CRISPR-Cas & restriction modification cell.com/cell-host-micr…

Thanks!!! Rafa Pinilla-Redondo Bruno Gonzalez Zorn really nice time. Congrats 🎊 Concha Ortiz PhD International thesis #MicroTM #INIBIC #SomosChuac #CRISPR

Phage-mediated peripheral kill-the-winner facilitates the maintenance of costly antibiotic resistance | Nature Communications nature.com/articles/s4146…

Delighted to have started my tenure as an editor for mBio journals.asm.org/journal/mbio handling papers on Streptomyces, natural product evolution and biosynthesis, experimental evolution, bacteriophage resistance, Corynebacterium and engineering biology

Featured Article: Phage DNA modifications evade defense Phage DNA modification adds arabinose to cytosines via hydroxy linkage(5ara-hC) w/potential double/triple arabinosylation. Arabinosylated phages are protected from CRISPR-Cas &restriction modification cell.com/cell-host-micr…

A bacterial host factor confines phage localization for excluding the infected compartment through cell division: Cell Reports cell.com/cell-reports/f…

Advanced research and exploration of CRISPR technology in the field of directed evolution sciencedirect.com/science/articl…

Phage counter-defense repertoires: New work IDs broad & specific anti-defense genes in variable regions of Pseudomonas phage genomes. Inhibitors neutralize diverse bacterial immune systems, highlighting how phages evolve broad & specific strategies cell.com/cell-host-micr…