So many “UTIs” that turned out to be HSV encephalitis. As Emily Moin said, just because a test is negative doesn’t mean it wasn’t indicated

We investigated whether HSV encephalitis is associated with having systemic autoimmune disease or exposure to immunosuppression. In the Medicaid dataset, there was a positive association on both counts! neurology.org/doi/10.1212/WN…

Happy to share Laura Cacciaguerra et al study of #MOGAD lesion changes during attacks: ➡️ 10% of attacks have an initial normal MRI (radiologic lag) ➡️ MRI more dynamic than in #MS or #NMOSD with T2-Lesions often appearing & sometimes resolving within attacks👇neurology.org/doi/10.1212/WN…

With the advent of BTK inhibitors in MS, we’ll have to be even more careful and advise patients on the risks

In a recent study published in the Journal of Brain, Behavior, and Immunity, researchers from MGH Neurology and colleagues investigated MS and synapse damage from inflammation. Read more: massgeneral.org/news/research-… @mghneurosci

Among 258 people with #MultipleSclerosis treated with monoclonal antibodies (natalizumab, ocrelizumab, ofatumumab, rituximab), 54.7% had wearing-off phenomenon, along with depression and poor treatment satisfaction. Online survey from Cleveland Clinic ▶️ journals.sagepub.com/doi/full/10.11…

His portrait hangs in the hearts of his students. "Si monumentum requiris circumspice."

Very grateful for the support of Banting Canada for my postdoctoral fellowship. I will studying the role of gamma delta T cells in MS. Also incredibly grateful to my mentors Michael Levy, MD, PhD Shamik Bhattacharyya for their support! Stay tuned! Brigham and Women's Neurology Harvard Medical School

Congratulations to Shamik Bhattacharyya, the inaugural incumbent of the Anne Finucane Distinguished Chair in Neurology. Dr. Bhattacharyya was celebrated during an event on May 20th.

Great thread! Would also mention tocilizumab as an acute treatment for fulminant ADEM esp if intracranial hypertension. neurology.org/doi/10.1212/NX…

This! Always keep MOG on your differential for cortical encephalitis and remember it may not be on the autoimmune encephalopathy panel (for Mayo it is not).

#RTwitter, any straightforward way of incorporating iptw weights into brms when doing a Bayesian analysis?

🔍Editor’s Choice Paper 🛎️Welcome to this review "The Impact of Anti-Amyloid Immunotherapies on Stroke Care". ✍️by Phil Bilodeau, MD et al. Mariel Kozberg 🔗More details: mdpi.com/2687472 MDPI Medicine & Pharmacology Harvard Medical School #mdpijcm #Stroke #neurotwitter

Interesting study. Need to be careful though with potentially overinterpreting this and other retrospective observational studies purported to prove the effectiveness of early PLEX. My detailed rapid response to this article is here: jnnp.bmj.com/content/early/…

If you treat MOGAD patients, check out our editorial on B-cell depletion in MOGAD! msard-journal.com/article/S2211-…

Absolutely brilliant read from Tom Pollak about the dangers of attributing everything to inflammation. I would add that we, as a field, cannot even agree on what constitutes pathologic inflammation. academic.oup.com/brain/article/…

I make a point of deleting the handedness out of every one-liner…Mostly useless piece of information which only bloats the notes

I am very grateful to The Patient-Centered Outcomes Research Institute for funding our clinical trial on the comparative effectiveness of immunotherapies in NMOSD. Huge shout-out to our entire team: The Sumaira Foundation, Prof. Friedemann Paul, and Dr. Marcelo Matiello, without whom this would not have been possible.