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#WorldAlzheimersDay is an inspiring reminder that hope is on the horizon. Brilliant scientists all over the world are working hard to stop Alzheimer’s disease—and they’re making terrific progress.

To join the community and get the latest news, visit our website. epnd.org #WeAreEPND #EPND

In pairs of identical twins, tau tangles accumulate in strikingly similar patterns, but stage of #alzheimersdisease and lifestyle can still make a difference. @vuamsterdam ow.ly/e1Tc50HCIZM

Updated prevalence estimates of amyloid abnormality from the Amyloid Biomarker Study Group now available including data of 19097 participants from 85 cohorts!

CSF tau levels reflect much more than neurodegeneration only: see Pieter Jelle Visser MD PhD latest CSF proteomics study in EMIF-AD MBD Neuronet European Platform for Neurodegenerative Diseases & ADNI; #memorabel ZonMw

In #Alzheimers disease, levels of CSF tau are related to neuronal plasticity protein concentration. Individuals with high tau show increased levels of these proteins while those with normal tau have decreased levels. Perhaps treatment of AD must differ depending on tau levels?

Proud to announce the #EPND Cohort Catalogue! Search the catalogue and filter by metadata on research participants, #biosamples, cognitive data, & more. Discover 60+ European cohorts, and create new collaborations for your #neurodegeneration research. ➡️discover.epnd.org

A fantastic #milestone to mark the first year anniversary of European Platform for Neurodegenerative Diseases. Many thanks to all the partners in this consortium for making this happen. Looking ahead to the best year. Alzheimer Europe Innovative Health Initiative Pieter Jelle Visser MD PhD Alzheimer's Disease Data Initiative

Data and sample sharing as an enabler for large-scale biomarker research and development: The EPND perspective frontiersin.org/articles/10.33…

Research by Betty Tijms 's team Pieter Jelle Visser MD PhD Alzheimercentrum Amsterdam (inactief) Sebastiaan Engelborghs : "CSF Proteomic #Alzheimers #Disease-Predictive Subtypes in Cognitively Intact Amyloid Negative Individuals" #Cognitive #proteomics 🔗mdpi.com/1213890 #mdpiproteomes via Proteomes MDPI

Read more in Frontiers - Neuroscience on how European Platform for Neurodegenerative Diseases and partners are addressing challenges hampering large-scale research for neurodegenerative diseases. addi.pub/addiepndtw123

With support from Innovative Health Initiative, we’re building a platform and community to fuel new discoveries and accelerate the development of diagnostics and treatments. Together, we can change the future of #Neurodegenerative diseases.

Een #concert om niet te vergeten: ma. 15 mei bundelen topmusici en topwetenschappers hun krachten voor meer aandacht voor de ziekte van Alzheimer: optredens van o.a. pianiste Gvetadze nino en jong talent uit Oekraïne (9 jr.) concertgebouw.nl/concerten/2589… 📷sarah wijzenbeek & Daan Brand

Collaborative research can accelerate the discovery & validation of neurodegenerative disease #biomarkers. So, to support researchers, we are developing guides & protocols to complement our technical infrastructure for sample & #DataSharing. Read more about our SOPs!⤵️ (1/5)

#Biomarker assays must be validated to ensure they provide reliable, accurate results 📄 To guide researchers, our validation SOP details specific procedures for technical validation of fluid-based biomarkers🩸 (3/5) epnd.org/resources/deli…

Our report on best practices for biobanking draws on the expertise of leading #biomarker researchers and biobanks 🧪 Read our guidance on certifications, clinical procedures & laboratory protocols, covering the A-Z of biobanking activities➡️ (4/5) epnd.org/resources/deli…

Cerebrospinal fluid proteomics parsed #Alzheimersdisease into five subtypes. Each was associated with distinct genetic risk variants, degrees of brain atrophy, and disease duration after diagnosis. Amsterdam UMC Maastricht University ow.ly/r33r50Qgu15

Breaking down #Alzheimers disease into 5 subtypes by proteins in cerebrospinal fluid, with distinct genomic profiles and molecular processes nature.com/articles/s4358… Nature Aging Pieter Jelle Visser MD PhD Betty Tijms

📢 Announcing a new edition of our e-Newsletter! We're delighted to share the latest updates from EPND, including a special Catalogue feature, research news, partner interviews and much more 📰 Read the newsletter ➡️ mailchi.mp/epnd/newslette…

📢The @IMI_EPND Hub launches today! With powerful new features for #neurodegeneration researchers and cohorts, the EPND Hub streamlines discovery, access, sharing and analysis of biosamples and datasets 🤝 Learn more and join the EPND community ➡️ epnd.org/news/epnd-laun…