Our new paper, "NK2R control of energy expenditure and feeding to treat metabolic diseases," is out today in nature. Here we identify a single receptor that can both peripherally increase energy expenditure and centrally suppress appetite. nature.com/articles/s4158… 1/12 🧵👇

Nice to see Puigserver Lab publication on respiratory complex adaptation to cold in this focused issue!!

Very thankful for the invitation to participate at the Rising Stars symposium on obesity and diabetes University of Kentucky College of Medicine. Nice discussions and future challenges in the field.

Very interesting findings on the epigenetic memory of fat cells and the control of body weight homeostasis.

Nature research paper: Adipose tissue retains an epigenetic memory of obesity after weight loss go.nature.com/4eJizC8

Agalya Periasamy et al.: Structure of an ex vivo Drosophila TOM complex determined by single-particle cryoEM #MitochondrialTranslocases #SingleParticleCryoEM #TOMComplex @unimelb ANU Media... #IUCr journals.iucr.org/paper?S2052252…

Many thanks to The Martin Ott lab for highlighting our paper!

Dana-Farber Cell Press Pedro Latorre Muro Thank you Dana Farber Editorial Team for writing this blog on this article blog.dana-farber.org/insight/2024/1…

Very excited to start 2025 sharing our latest work Puigserver Lab published in Nature Cell Biology! We have shown that the cytosolic chaperone PPID/CYP40 inserts TOM70, connecting chaperones and mitochondrial protein biogenesis to the development of chronic metabolic disorders!

Congratulations! Excited to announce the new publication in Nature Cell Biology by Pedro Latorre Muro Puigserver Lab I had the privilege of participating in this work during my stay at the Dana-Farber

Cardiolipin deficiency disrupts CoQ-complex III interface in steatohepatitis biorxiv.org/content/10.110…

New studies from our lab by Tevis Vitale and Jason Liang published in Nature Cancer Selective deficiency of mitochondrial respiratory complex I subunits causes tumor immunogenicity through T cell surveillance and Immune Checkpoint Blockade responsiveness rdcu.be/d6BgJ

After much anticipation, I'm glad to say that the first paper from my Ph.D. is now out in Nature Cancer! Thanks to all the co-authors for their input and hard work! nature.com/articles/s4301… Below is a 🧵detailing our results 1/7

Fresh out of the press! ✨Check out our new paper on the violent entry of the HIV capsid into the nuclear pore — watch it crack that gate! 🤯 💥 Incredible work from Beck Laboratory and Hummer Lab 🤩 More here: biophys.mpg.de/2842024/hivcap… 🔗

Very exciting avenues connecting mitochondrial ETC dysfunction and cancer immunogenicity Puigserver Lab Tevis Vitale Jason Liang

💫NEW by Puigserver Lab & co: the chaperone PPID drives insertion of the #mitochondria import receptor TOM70 into the mitochondrial outer membrane, regulating body temperature, glucose homeostasis and body weight in #obese mice. 👉rdcu.be/d8atv nature.com/articles/s4155…

Happy to share the new publication from our lab, identifying a new assembly factor of CI involved in disease!!!‼️🚨#mitochondria Time-resolved mitochondrial screen identifies regulatory components of oxidative metabolism | EMBO reports embopress.org/doi/full/10.10…

New preview just published in Molecular Cell! We highlight exciting work by Chen et al. identifying an arginine sensing axis mediated by BAG2 and SAMD4B that promotes survival under arginine deficiency. authors.elsevier.com/c/1lN5t3vVUPVa…

Happy to share our manuscript published today on regulation of cardiac adaptation to exercise training by PGC-1α and GDF15 in Nature Cardiovascular Research! nature.com/articles/s4416…

The Khetarpal lab at UVA is seeking a research associate (postdoc)! Please see the posting and reach out with any questions! jobs.virginia.edu/us/en/job/R007…