Andrew Poesaste (@poetential) 's Twitter Profile
Andrew Poesaste

@poetential

🇦🇺 🇬🇧. Partner at @rampersand_fund. Prev @angularventures. Dad. Husband. Tech Nerd. Early adopter, hopeful Knicks fan, globe wanderer, foodie, DMs open.

ID: 83906314

linkhttps://apoe.substack.com/ calendar_today20-10-2009 19:14:46

7,7K Tweet

1,1K Followers

4,4K Following

Andrew Poesaste (@poetential) 's Twitter Profile Photo

The super app health space, pursuing Peter Attia's 3.0 Medicine: proactive health, is interesting. Different attack vectors, with a few companies trying to go from lab (Neko Health, Biograph, Everlab) to consumer. Others from the consumer app (Superpower) to partner labs.

Andrew Poesaste (@poetential) 's Twitter Profile Photo

The game is afoot: Google back in Founder Mode (+Demis) and OpenAI going for it all, with hardware, app layer. Apple’s App Store and Google search getting heat. Competition is great, open season.

Andrew Poesaste (@poetential) 's Twitter Profile Photo

What an incredible video. It has it all. A rallying cry about SF the city, culture, the art of the possible, Jony and Sam, tech optimism and future products. youtube.com/watch?v=W09bIp…

What an incredible video. It has it all. A rallying cry about SF the city, culture, the art of the possible, Jony and Sam, tech optimism and future products. 

youtube.com/watch?v=W09bIp…
Amjad Masad (@amasad) 's Twitter Profile Photo

Denial is a silent killer of startups. Almost every major change we made at Replit came later than it should have because it was too painful to come to terms with reality. That’s why today one of our operating principles is SEEK PAIN.

Andrew Poesaste (@poetential) 's Twitter Profile Photo

"Come for the notes, stay for the workflow" - still one of the most underrated wedge strategies. Start with the simple, perfect note-taking, then expand into sticky workflows that actually run the business: billing codes, compliance tracking, team handoffs, audit trails.

Andrew Poesaste (@poetential) 's Twitter Profile Photo

Watching every climate startup rebrand in real time: Climate → “supply chain resilience” Clean energy → “energy security” ESG → “operational efficiency”

Andrew Poesaste (@poetential) 's Twitter Profile Photo

Sad day for those devs who didn't want to learn new frameworks and decided to make bulk $£ by mastering Cobol: Morgan Stanley has a new way of using AI to modernize legacy software wsj.com/articles/how-m… via The Wall Street Journal

scott belsky (@scottbelsky) 's Twitter Profile Photo

Anticipated and referred to this as the impending “data wars” in previous edition of Implications, but didn’t expect it to start this quickly… Data grab and protectionism underway, especially by those that don’t own their own graphs or sophisticated permissioning layers.

Andrew Poesaste (@poetential) 's Twitter Profile Photo

I’ve always believed a small subset of talent is wildly underpriced. The founders of the world’s biggest platforms know it. Zuck maybe more than anyone on the planet.

Andrew Poesaste (@poetential) 's Twitter Profile Photo

I keep hearing engineering teams rave about Claude Code (even the sceptics). The $200 monthly max contract is the right plan to maximise token usage - otherwise, you could blow through the base plan ($20) in 15 minutes.

Andrew Poesaste (@poetential) 's Twitter Profile Photo

Fine-Tuning LLMs is a Huge Waste of Time, by Devansh: Machine Learning Made Simple- Fine-tuning advanced LLMs isn’t knowledge injection — it’s destructive overwriting. …dinginterviewsmadesimple.substack.com/p/fine-tuning-…

Andrew Poesaste (@poetential) 's Twitter Profile Photo

I know you can’t publicly utter the question ‘But what about the investors?’ But what happens to them in the Windsurf situation? 0? With the talent land grab packages so high, the company valuation has to be much higher than the team size * AI comp package otherwise just leave?🤨

Andrew Poesaste (@poetential) 's Twitter Profile Photo

Seeing multiple companies build tools like Cluely for universal conversation context - real utility there (think about calling your doctor or a supplier). But I'm curious if the 'cheater' positioning is genius marketing or will hurt the enterprise in the long run.

Erik Bernhardsson (@bernhardsson) 's Twitter Profile Photo

Hypothetical question, inspired by current events: if you’re a CEO and you tell a company: don’t acquire us, just hire me and my top people for half the price. That’s a breach of fiduciary duty to the shareholders right?

villi (@villi) 's Twitter Profile Photo

The Blitzhire Acquistion. In this blog post I try to explain the drivers behind these new strange acquisitions in AI, how these deals are structured and why, where the money goes and how, and what happens to the remaining employees. Feedback is welcome. medium.com/@villispeaks/t…

Andrew Poesaste (@poetential) 's Twitter Profile Photo

I propose we call them HALO deals. “Halo” comes from “Hire and license out. People with halos have left their bodies to live somewhere in the cloud giants. - new Kevin Kwok kwokchain.com/2025/07/15/the…

BuccoCapital Bloke (@buccocapital) 's Twitter Profile Photo

Hey. Hey kid. A bit of free advice. Just go get a job at the two hottest, most competitive startups in the entire world. Aw. Shit. Don’t thank me. I just love to help people. What can I say? Let me know if I can ever be helpful.