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Now online EMBO Reports : More insights into the importance of body temperature cycles: How alternative splicing coupled to decay (#NMD) can generate rhythmic gene expression (#circadian)! Thanks to our collaborators from #sfb973 and #Omiqa embopress.org/doi/full/10.15…

Very interesting review. Worth a read: nature.com/articles/s4157…

Have you noticed it’s getting chilly in the air? How are plants coping with this? Happy to share the remarkable work of David Guillaume-Schöpfer, who did his PhD in the group, and our amazing collaborators Webb Lab Alex Costa Fabrizio G. Doccula Jaeger lab 🇮🇱🇺🇦 biorxiv.org/content/10.110…

Curious about how reovirus can survive in a low-pH environment? Find out more about it in my latest publication on bioRxiv. Thanks to Max Ruwolt and all AG Neu for making this possible!

For the first time, researchers have revealed the atomic structure of the human minor spliceosome, according to a new study in Science. The findings provide a framework for a mechanistic understanding of the function of this ribonucleoprotein complex. ($) fcld.ly/xgmy6w2

The popularity of selected methods for differential #splicing identification. #bioinformatics #methodsmatter

Are stress granules the RNA analogs of misfolded protein aggregates? Both RNA and proteins can form promiscuous interactions. Similar to the protein chaperones, the RNA chaperones limit self-assembly. #RNASpecialIssue #condensates ➡️bit.ly/32JtPz0

Here comes the second one from @AlexandraBergf1 . This time also including the great support from Marco (Marco Preußner) from the lab of Florian Heyd Biochemistry FU Berlin . Happy to be part of this work 🥳 nature.com/articles/s4146…

Now online Nucleic Acids Res: How a 1°C increase in temperature induces antiviral genes and promotes an immune response! Great work from Bruna Los! doi.org/10.1093/nar/gk…

Ever wonder what happens to our brains at lower temperatures? Looks like our neurons enjoy a cool bath – thanks to increased expression of a cold-shock protein, RBM3. Check out our preprint sharing some secrets behind RBM3 cold induction. biorxiv.org/content/10.110…

GGGOOOAAALLL we made the cover! huge thanks to the team NatureStructMolBiol Sara Osman for highlighting our work! nature.com/nsmb/volumes/2… 🤩😍🥰😊🥲 feelin' all the feels 🥲😊🥰😍🤩

Our next RNA club meeting today at 5 pm will feature the research of Marco Preußner from Heyd lab Biochemistry FU Berlin and Vanessa Loiacono from Bock lab MPIMP Potsdam Golm 🌱🧪. Join us in person or via zoom!

Now in Science Advances: Alternative splicing occurs after step 1 of splicing! Also reveals trans-acting factors for NAGNAG splicing. Thanks to Reinhard and his team, my phantastic students ⁦Biochemistry FU Berlin⁩ ⁦Freie Universität and help from @OmiqaBio DOI: 10.1126/sciadv.adf1785

Gene therapy approach to boost 'cold shock protein'€™ in the brain without cooling protects mice against neurodegenerative disease shar.es/afIZjj

Hypothermia in a syringe: Manipulation of RBM3 alternative splicing using antisense RNA therapeutics prevents neurodegeneration at normal temperature. Check our article with Mallucci Lab and @OmiqaBio in EMBO Mol. Medicine Link: doi.org/10.15252/emmm.…

📯 Our work on a new core splicing factor is out in Molecular Cell! FUBP1 is important for splicing of long introns. Multivalent interactions support spliceosome assembly and intron bridging. Great collab with @Sattler_lab & Luck_lab. Check it out here: bit.ly/4552p18

Please check out our new review on commonalities between vesicular and nonvesicular transport via intrinsically disordered proteins! Hope you will like it!

🎉Excited to announce that our paper on the blueprint of the human spliceosome is now out in Science Magazine ! A decade of work with Juan Valcárcel and the incredible team at Centre for Genomic Regulation (CRG) to uncover the intricate roles of this essential RNA machinery.science.org/doi/10.1126/sc…