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Very excited to present a @bioRxiv paper from our lab on our human organoid tumor transplantation (HOTT) system to study glioblastoma! This work was led by the very talented project scientist Dr. Weihong Ge + exceptional graduate student Ryan Kan (1/18) biorxiv.org/content/10.110…

Delighted to share our most recent preprint led by the incredible Jessenya Mil and Jose Soto! In this study, we generated a metabolomic atlas of human cortical development and discovered that the pentose phosphate pathway regulates radial glia cell fate. biorxiv.org/content/10.110…

Excited to present our new preprint led by Claudia Nguyen uncovering how thalamic input shapes human cortical development! We discover that thalamic axons promote upper layer cortical neurogenesis through NRXN1-mediated contacts with outer radial glia. biorxiv.org/content/10.110…

🧵Excited to share our new preprint introducing iHOTT - an autologous tumor-immune co-culture model that captures patient-specific responses in #Glioblastoma 💥Now on bioRxiv: biorxiv.org/content/10.110… 📝From Aparna Bhaduri in collaboration with UCLA Neurosurgery 🧠