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Exercise is even better in increasing insulin sensitivity in muscle than we thought:

Our quest to save exploratory human physiology from suffocating clinical trial registration.

New look at AMPK!

Congratulations, very well deserved!

Great meeting!

How can women possess similar or even greater whole-body insulin sensitivity, while at the same time typically have less muscle mass and more fat mass than men with the same BMI? We investigated this in our most recent work: faseb.onlinelibrary.wiley.com/doi/10.1096/fj… @BiomedUCPH Novo Nordisk Foundation

Very happy to see this huge project finally published and grateful for a terrific collaboration with Katrien De Bock @debocklab and others. Started with a simple question whether GLUT1 is necessary for glucose transport out of muscle capillaries but spiralled into inflamation.

Do you feel you know GDF15? Some unanswered questions for you! authors.elsevier.com/a/1k07M3jDgWq3…

Have you ever doubted the importance of muscle health in type 2 diabetic risk? Check out our latest human study published in Nature Metabolism to see if we’ve cracked the code using a state-of-the-art recall by genotype and deep metabolic phenotyping nature.com/articles/s4225…

Newest insight in exercise effects on muscle insulin action in men with normal and decreased insulin sensitivity.

Our new FASEBJ paper. We looked into mTOR Ser1261 phosphorylation in human and mouse muscle, proposed by Diane Fingar's lab to be first an Akt and then AMPK site regulating mTORC1 and 2 activity. Clearly AMPK site but impact on mTORC unclear in our hands faseb.onlinelibrary.wiley.com/doi/10.1096/fj…

Breakthrough science!

Fascinating role os a mechanoreceptor in adipose tissue

Fascinating how reducing protein intake increases energy expenditure in men and mice regardless of whether protein in the diet is replaced by carbohydrate or fat.

Our new paper in Redox Biol showing that insulin stimulation of skeletal muscle surprisingly does not detectably increase the ROS H2O2 using state-of-art methods in different models including humans, but in fact causes a selective reductive shift sciencedirect.com/science/articl…

So well deserved, Lykke is a star!

Our most comprehensive review ever! With twiterless Amira Klip and Philip Bilan. #nexs A Comprehensive View of Muscle Glucose Uptake: Regulation by Insulin, Contractile Activity and Exercise | Physiological Reviews | American Physiological Society journals.physiology.org/doi/abs/10.115…

GDF15 is still a mystery hormone: Trends in Endocrinology & Metabolism Now finally out in print! cell.com/trends/endocri…

Our most comprehensive review ever, now out in print. Hopefully a good ressource for many. Great collaboration with Phil Bilan and Amira Klip.