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Great work by Dominik Groos from the Helmchen Lab on hypothalamus–habenula circuits!

If you want to understand the brain, should you work as a neuroscientists in the lab? Or teach the subject for students? Or simply read textbooks and papers while having a normal job? In this blog post, I share some thoughts on this topic. gcamp6f.com/2025/01/08/ann…

I want to highlight *some* of my favorite studies on dendrites and spines from 2024 👀 - feeling very excited and inspired about the field 🔥 Happy new year y'all!

Hive mind: Has anyone seen myelinated synapses before? Or what do you think this is?

A Sensitive Soma-localized Red Fluorescent Calcium Indicator for Multi-Modality Imaging of Neuronal Populations In Vivo. It works well with wide-field imaging, two-photon microscopy, and fiber photometry biorxiv.org/content/10.110…

If you haven’t seen it yet, check out our paper on multimodal mismatch responses, which is now out in eLife. Thank you to the eLife - the journal editorial team and reviewers for a pleasant and constructive revision process. elifesciences.org/articles/95398

New blog post on how to use Google Scholar as a scientist: - Create a Google Scholar profile - Curate your publications - Annotate shared first authorships - Follow related research gcamp6f.com/2025/02/18/how…

I couldn't find a short video showing action potentials evoked by optogenetics, so I made one. youtu.be/bPEV9tI1gRQ?si…

I am very proud to announce that my PhD paper finally came out in Cell! In this *very* collaborative study, we develop and release a deep-learning approach to predict neuron type identity from their electrical signature. doi.org/10.1016/j.cell… 1/16 🧵

Prediction of neuronal cell types based on electrophysiology with optotagging ground truth - this looks pretty useful!

👀 We hit a major milestone: the PR for DLC3 is merged into main, and rc7 is up for final testing: pypi.org/project/deepla… - this is the most powerful, most new-user (+ new GUI features!) & ML expert friendly code, & the highest performance ... ready to #AnimalPose?! 🚀

How much analgesia is needed to manage pain levels in mice after brain surgeries? A single dose of meloxicam seems to be enough. Even the addition of opioids cannot provide a clear benefit (in line with recent work from others, see refs in our preprint): biorxiv.org/content/10.110…

New blog post: Non-linearity of calcium indicators - history-dependence of spike reporting gcamp6f.com/2025/03/14/non…, highlighting an interesting analysis of our recent preprint.

Our latest research, led by Antoine Madar, on what #SynapticPlasticity rules shape CA1 and CA3 representations in the hippocampus during familiarization has just been published in Nature Neuroscience! Read here: nature.com/articles/s4159…

How do you compute ΔF/F in calcium imaging? 🧠🔬 It’s not one-size-fits-all! Learn why GCaMP behaves differently and how to adapt ΔF/F calculations to your data. Read more from Peter Rupprecht, University of Zurich . buff.ly/jzmY5vj #Neuroscience #CalciumImaging

The BlueSpot Talk is a seminar series about the locus coeruleus organized by David Weinshenker. Today at 11 AM EST or 5 PM CET, I'll give a talk: "Effects of locus coeruleus on hippocampal astrocytes and neurons during natural and artificial arousal" zoom.us/j/99332227402