🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Researchers reported for the first time that miR-7 could target Akt3 and interact with genes in the p53 pathway to suppress the development of #NSCLC. 🫁 🔓 bit.ly/40zHFPn

A team at the Mayo Clinic used #multiplex imaging to study the spatial organization of long cells and tissues in #asthma and #COPD. 🔬 📖 Respiratory Medicine Portfolio: bit.ly/4eB8CrL

Interested in #COPD, #PulmonaryFibrosis, or #LungCancer research? 🫁 Pulmonary Cell News delivers the latest updates on pulmonary disease and cell biology. Don't miss out on these updates! Subscribe here: bit.ly/4kkWMEu

Researchers at the University of Ulsan designed hybrid #nanoparticles containing #dexamethasone and monophosphoryl lipid A, which targeted dendritic cells and macrophages in a mouse model of #asthma. 📑 ACS Nano - bit.ly/4lhxwz5

This #review summarizes recent advances and challenges in cell-based immunotherapies for #LungCancer. 📍Read it here: bit.ly/4lQiUa3

How can PLGA #Nanoparticles improve #DrugDelivery to the lungs? 📦 This #review focuses on their potential to enhance inhalation therapy formulations. 👃 bit.ly/3TSFItT

🦛 Heterogeneous Hippo pathway (YAP/TAZ) activation in lung #adenocarcinoma drives tumor progression by enabling ferroptosis resistance via non-cell-autonomous mechanisms. Learn more in EMBO Reports: bit.ly/4lLCtQz

Dr. Pau Castel's team at NYU Grossman School of Medicine documented the diversity of RIT1 mutations in human #LungCancer and showed that physiological expression of RIT1 M90I is sufficient to drive autochthonous lung tumor development in vivo in mouse models. 🐭 bit.ly/3Gpu5HL

A research team from MD Anderson Cancer Center (MD Anderson Cancer Center) shows that KEAP1-NRF2 pathway drives a compensatory modulation of ATR-CHK1 signaling, enhancing vulnerability to ATR inhibitors. 🔓 bit.ly/3UcDBAX

Asiaticoside mitigates #COPD by modulating TRIM27 stability and activating PGC-1α/Nrf2 signaling, reported scientists from Jiangnan University. 💡 Learn more: bit.ly/4lZbPUD

⚗️ Researchers suggest that H ferritin subunit silencing can be an effective anti-tumor strategy to enhance the activity of JQ1, BET bromodomain inhibitor, acting to overcome the chemotherapy resistance in more aggressive #NSCLC. Università degli Studi Magna Graecia di Catanzaro bit.ly/44E4EeN

Researchers from Jiaxing University uncovered elevated levels of ERCC6L in #LUAD, significantly associated with unfavorable patient outcomes. 🩺 🕳️ Dig into the details: go.nature.com/414j3hS

Scientists including Dr. Byoung Chul Cho discuss the evolving roles of MET as a therapeutic target in #NSCLC and beyond. 🔎 Learn from their insights in NatureRevClinOncol: go.nature.com/3GYtAVa

This new FASEB study suggests that Sirt1 might prevent CREB enrichment by inhibiting histone acetylation in the Nr4a3 promoter, thereby suppressing Nr4a3 expression and ultimately attenuating acute lung injury. 🫁 bit.ly/44MsQf4

In a recent Nature Biomedical Engineering study, the Yokokawa lab/ Kyoto University presented human airway-on-chip and alveolus-on-chip models using lung progenitor cells derived from isogenic iPSCs. 🫁🧫 📚 Discover more: go.nature.com/4fcCqvk

Scientists elucidate the interplay between SLC7A5, mTOR signaling, and autophagy pathways, providing insights into potential strategies to overcome drug resistance in boronophenylalanine-boron neutron capture therapy. 💊 go.nature.com/3TUwSvF

New to air-liquid interface (ALI) cultures or PneumaCult™ media? Browse through these STEMCELL Technologies FAQs to find answers to commonly asked questions on culturing human airway epithelial cells at the ALI. 🫁 bit.ly/3R4TSGF

Activated Cdc42-associated kinase 1 inhibition (ACK1i) induced mitophagy through the release of RFX2 inhibition on BNIP3 transcription, thereby driving adaptive resistance. Inhibiting mitophagy sensitizes #NSCLC to ACK1i. 📚 More here: go.nature.com/4mhZPOe

This eLife - the journal study reports that phosphodiesterase 1A (PDE1A) promotes metastasis in #NSCLC cells, and PDE1A overexpression is correlated with #angiogenesis and poor outcomes of NSCLC patients. 🕳️ Dig into the details: bit.ly/45pYor8

How does TIGAR affect lung cancer? 🐯 Scientists show that TIGAR markedly inhibited glucose metabolism, ROS production, and susceptibility of lung cancer cells to cisplatin. 👉 bit.ly/4maP2Wx