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Some teaser images from Daniel Medina Cano and Tarek Islam. 4 day old mouse neural organoids generated from pluripotent stem cells. Green: ZO-1 (apical membrane) Purple: phospho-H3 (dividing cells) Red: Nestin Keep an eye out on Biorxiv in the coming weeks to learn more!

Excited to share the first manuscript from my team @sloankettering Center for Stem Cell Biology at Sloan Kettering! biorxiv.org/content/10.110…

Characterization of sequence determinants of enhancer function using natural genetic variation biorxiv.org/content/10.110…

Extremely thrilled to announce that our paper on deriving robust brain organoids and definitive endoderm from mouse epiblast stem cells is out in Development! I hope it becomes a great resource for the community journals.biologists.com/dev/article/14…

Excited to share our latest paper led by Rachel Glenn. We generated a genetically diverse mouse pluripotent stem cell panel from the Diversity Outbred stock and outline experimental approaches for "population-scale" in vitro directed differentiation. biorxiv.org/content/10.110…

Excited to share our latest manuscript. This was an exciting collab with the (twitter-less) Matthias Stadtfeld + Jason Mezey labs at Weill Cornell. We examined the impact of genetic variation on pathological loss of DNA methylation in naive PSCs. biorxiv.org/content/10.110…

Beyond excited to share my main postdoctoral work. We developed a robust mouse cortical organoid system, which recapitulates in vivo tempos and cellular diversity, and applied it to identify gene expression changes across subspecies during development. shorturl.at/9w0zT

Excited to share the latest work from my lab and Emily Wong led by Daniel Medina Cano Tarek Veronika Petrova. We developed a new protocol to generate mouse cortical organoids from pluripotent stem cells. Memorial Sloan Kettering Cancer Center Center for Stem Cell Biology at Sloan Kettering MSK ScienceEducation biorxiv.org/content/10.110…