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Super cool observation that a monogenic mechanism of longer telomeres yields familial clonal hematopoiesis of indeterminate potential. nejm.org/doi/full/10.10… NEJM This is super cool bc it's not the expectation as Gina Kolata The New York Times explains (nytimes.com/2023/05/04/hea…) 🧵👇

What techniques are folks using to help trainees get to a first draft (especially for their first paper)? Here's my lab handbook page on writing, but the tips are mostly technical. What's the big picture advice for going from an outline to a full paper?

What an exciting #ISIDTokyo2023! Was honored to share our work on somatic mutations in prurigo nodularis with Dr. Shawn Kwatra, celebrated two great plenary talks Katie Roster Jay Patel, and met the most generous couple who treated me to new sushi varieties 🥹🍣! Arigatou, #Tokyo

At both 12 and 24 weeks, those who were randomized to spironolactone had significantly greater improvement in their AcneQoL scores compared to those randomized to placebo. However, the absolute differences were relatively small. 6/14

"Overall, compared with tumor mutational burden, the structural variation analyses revealed a much more widespread pan-cancer effect, with larger increases per metastatic cancer type that affected almost every cancer type studied." nature.com/articles/s4158… #cancer #genomics

Are you better off being taken care of by an MD or DO? Bryan Carmody & I had the honor to discuss the recent Annals of Int Med paper that found no differences in 30-day mortality,🏥 readmissions, LOS, or health care costs between MD and DO's... acpjournals.org/doi/10.7326/m2… A quick 🧵...

So grateful for your mentorship and support Dr. Shawn Kwatra Incredibly honored to share our creative analysis of somatic mutations in prurigo nodularis. Check out the preprint and overview below! 😊 #MedTwitter #dermtwitter

Very excited by our results nature showing that IL4R signaling is strongly enriched in myeloid cells that infiltrate mice and lung cancer lesions nature.com/articles/s4158…

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Excited to share our JAMA Dermatology viewpoint bitly.ws/3fSDp examining immunotherapy in localized melanoma. Big congrats to Hannah Rashdan in my lab for leading the piece, which was also a hot topic @ the most recent Melanoma Research meeting! Thx to Ade Adamson, MD MPP for his collab.

Last year, we did not match. This year, my wife matched in dermatology at UC Irvine, and I matched in ophthalmology at UCLA. During the reapplication process, we received the greatest gift from God, our son, who has brought us immense joy. Thank you everyone! #Match2024

Our study led by Buu Truong leverages the full corpus of polygenic risk scores to construct the best performing PRS for a target population cell.com/cell-genomics/… Cell Genomics Check out 🧵👇 by Buu Truong

Radiation recall is a fascinating clincal phenomenon that I learned about during clinic when I first visited WashU Medicine Division of Dermatology. Here in JAMA Dermatology we report on a case of radiation recall with two BTK-inhibitors. Many many thanks to Dr. Anadkat and Dr. Ferree. #MedTwitter #dermtwitter

Very excited to share our Delphi consensus guidelines to diagnosing dermatologic immunotherapy toxicites. Incredible team effort from more than 30 experts, including Steven Chen 陳持威, MD, MPH, MHPEd Kerry Reynolds, Jarushka Naidoo, and Nicole LeBoeuf.

Genetic variation is relatively poorly studied in the Middle East, particularly where endogamy and consanguinity are more common. Among 6K WGS in Qatar, 2 in 3 (!) was a carrier for a pathogenic mutation for an autosomal recessive condition. link.springer.com/article/10.118…

Extremely proud of the team, especially Guihong WAN, Sara Khattab, MD, and Wenxin Elmon Chen for our The Lancet Oncology study on multi-organ toxicities from checkpoint blockade, providing a roadmap for prognosticating outcomes via the lens of immunotherapy toxicities: tinyurl.com/yc3t7amf