REGISTRATION OPEN - CNIO meeting, Machines acting on DNA and RNA, 2025 May 28-30th in Madrid, organized by The Nogales Lab , Rafa F Leiro , Llorca lab Bringing leaders in structural biology in Chromatin structure, DNA repair, RNA processing, Replication, Transcription and Translation.

New Year, new beginnings... but first, I would like to THANK everyone I've crossed paths with during the last 8.5 years at The Sainsbury Laboratory John Innes Centre 🧵 (1/8)

In the end, I just want to say a big THANK YOU to all my mentors and friends for shaping my journey in Norwich into such an incredible and enriching experience! (8/8)

We're thrilled to present ESM3 in Science Magazine. ESM3 is a generative language model that reasons over the three fundamental properties of proteins: sequence, structure, and function. Today we're making ESM3 available free to researchers worldwide via the public beta of an API

Interesting in learning to process cryo-ET data in the latest version of Warp? I'll be running a workshop on April 22nd in central London, UK details+registration: forms.gle/u4Hk73jhenMvpN… Hope to see you there!

🧬 Roger Castells es doctor en Bioquímica y uno de los 374 investigadores del programa Construyendo la Generación IA, impulsado por Red.es. Actualmente lidera un grupo en CNIO Stop Cancer que diseña terapias contra el cáncer usando #InteligenciaArtificial👇

El #CNIOStopCancer crea ‘nanopartículas de proteínas’ para acelerar el desarrollo de fármacos contra el cáncer y detectar antes la enfermedad. Es el objetivo del nuevo Grupo de Diseño Biomolecular y Nanomedicina Estructural, dirigido por Roger Castells-Graells  bit.ly/4451iQc

El CNIO Stop Cancer crea ‘nanopartículas de proteínas’ para acelerar el desarrollo de fármacos contra el cáncer saludadiario.es/investigacion/…

Roger Castells-Graells, Premio HAWK Biosystems de la Soc Biofísica España a la trayectoria de investigadores de menos de 33 años en el campo de la biofísica.  Roger Castells-Graells dirige el Grupo de Diseño Biomolecular y Nanomedicina Estructural de #CNIOstopcancer. bit.ly/3ZTn4Ft

Honored and grateful to receive the HAWK Biosystems Award from SBeS 🙏 Thank you very much for this recognition!

¡No te pierdas las 📰​#NoticiasBreves_iSanidad de hoy! Soc Biofísica España Roger Castells-Graells CNIO Stop Cancer Partido Popular ESTER MUÑOZ Alberto Núñez Feijóo anefp mufaceoficial Edelman Spain Sanitas isanidad.com/336279/noticia…

Verano de bachillerato en el laboratorio: Aitana Soler y Jan Magem viven la realidad de la investigación científica en #CNIOStopCancer con el programa ‘Jóvenes y ciencia’ de la @FCLP_Fundació. Han trabajado un mes en el grupo de Roger Castells-Graells, que también participó en este programa

🔬 En el marco del #DíaMundialDeLaInvestigaciónContraElCáncer compartimos la historia de Pablo, investigador del CNIO Stop Cancer. 🙌Su misión: usar la #InteligenciaArtificial para crear nuevas proteínas que ayudan a tratar tumores.

This October I’m drawing 1 molecule a day inspired by proteins in pdb Protein Data Bank rcsb pdb 💉🧬💻🔬💊🌱🧠🦠 Day 4 Prompt MURKY Pdb 8T1M Domain with unidentified function 1842 from pathogenic bacteria There are many proteins with known structures but their function remains murky Next DEER

We’re looking for an enthusiastic postdoc to join our team. 😊 The project focuses on protein design and cryo-EM applied to cancer research. 🔬🧪 Position funded for 3 years. Please share 🙏 Job description and details (deadline: October 11th): cnio.es/en/empleo/post…

Very cool to see this structure from Miller et al. from the Yeates Lab 🔬

🚨New paper! Generative models are often “miscalibrated”. We calibrate diffusion models, LLMs, and more to meet desired distributional properties. E.g. we finetune protein models to better match the diversity of natural proteins. arxiv.org/abs/2510.10020 github.com/smithhenryd/cgm