Our new paper is out today. We used CRISPR to uncover some really striking findings with several drugs and drug targets in clinical trials. Also, we accidentally found the first-ever inhibitor of the cyclin-dependent kinase CDK11. stm.sciencemag.org/content/11/509…

We are so proud to announce that Joey Azofeifa, our CEO and Founder, has been named to the #ForbesUnder30 list in Healthcare! We're feeling grateful for all the opportunities Arpeggio has had this year.

My favorite little biotech is growing ...

Our latest preprint is now in the bioRxiv! doi.org/10.1101/2020.0…

Fun working with Palmer lab on zinc remodeling

My second favorite little start up is starting to gain traction!

Congrats to my old friend Paul!

Always a great day when a former undergrad reaches their next milestone. Congrats Phil!

Incredibly excited to be selected as one of the Packard Foundation 2020 #PackardFellows! Such an honor to join this inspiring community of scientists as I further my research in genome evolution and #transposons. bit.ly/fellows20

Angelika was an amazing scientist and a fellow advocate for Down syndrome and aneuploidy work. This is a sad day for science.

We are hiring The HPC System/Software Administrator will be a key member of the BioFrontiers IT team, passionate about providing technical assistance, software management More information BioFrontiers Institute HPC System/Software Administrator jobs.colorado.edu/jobs/JobDetail…

Our most recent collab paper...

We collaborate with the Taatjes lab and look forward to working with applicants!

Another collaborator looking for good people!

BioFrontiers Institute HPC System/Software Administrator jobs.colorado.edu/jobs/JobDetail… We are still adding to our staff. Please check out our HPC position.

How is p53 regulated? Paper with Robin Dowell in PLOS Biology shows D40p53 isoform tempers WTp53 activity to allow input from other TFs. Surprisingly, D40p53 blocks WTp53-dependent eRNA transcription and prevents mRNA biogenesis despite pre-mRNA induction bit.ly/3kk7nBN

It's out (pubmed.ncbi.nlm.nih.gov/34370511/ )! Ever noticed that most host-pathogen studies are done with macrophages from immune compromised mice that lack functional NRAMP1? Well, if you are interested in metals at the host-pathogen interface, read on...1/

Locked out of the wetlab on account of the earliest COVID lockdown (in 2020) -- and one student turns the situation into a nice piece of work. Read our latest paper @ BMC Genomics rdcu.be/cIt2W

Are you a diversity scholar interested in data science and Down syndrome? Join us in July for a workshop! app.smartsheet.com/b/publish?EQBC…

Dowell dicing up the defense to win a corner kick #JustUs #GoPokes