John O'Sullivan
@realjosullivan
Heart Failure Cardiologist (Central Sydney Cardiology, Royal Prince Alfred Hospital) / Professor of Cardiometabolic Medicine (University of Sydney)
ID: 927459577246900224
06-11-2017 08:56:09
240 Tweet
269 Followers
421 Following
This is incredible! Differentiating enantiomers by mini mass spec alone. This breakthrough paves the way for true point-of-care analytics in the clinical arena. #PURSPEC #Pharmacometabolism Chenchenwenwen #PRECISIONCAREDIAGNOSTICS
Delighted to share our new publication on Clinical and Preclinical HFpEF: NAD+ repletion is superior to risk factor modification in HFpEF. Yen Chin Koay Charles Perkins Centre University of Sydney Sydney Health Sydney Local Health District The Alfred #Cardiometabolic #HFpEF #BairdInstitute
A cogent Editorial on our recent work in HFpEF. Sydney Health University of Sydney The Alfred Baker Institute #HFpEF #Cardiometabolic
Our live patient medication level platform in the clinic: a breakthrough in the practice of pharmacotherapy. xiaosuo wang Eric Topol Medscape theheartorg | Medscape Medical Xpress The BMJ Stanford Medicine Healio World Health Organization (WHO) U.S. FDA
Delighted to share our latest work: a state-of-the-art review on how best to leverage metabolism for better outcomes in Heart Failure European Society of Cardiology Sydney Health Charles Perkins Centre Yen Chin Koay Prof Francine Marques #Cardiometabolic Circulation Circ: Heart Failure academic.oup.com/cardiovascres/…
Our latest work: SDGV, a new diagnostic biomarker of liver fat that outperforms all current biomarkers. Charles Perkins Centre Sydney Health Sydney Uni Media University of Sydney cell.com/iscience/fullt…
An honour to be invited to speak at Europe’s top hospital, Charite, by Gabriele Schiattarella Charité BIH Innovation
John O'Sullivan Charité BIH Innovation Great having you here John O'Sullivan! Everyone - especially the ECIs - loved your talk CRC1470
Myocardial proteomic and metabolomic analysis of PPCM reveals unique remodelling and metabolic changes not seen in DCM. John O'Sullivan crisdosremedios ahajournals.org/doi/10.1161/CI… #AHAJournals
Very productive meetings with Roman Rodionov, Stefan Bornstein, and Nikos Perakakis and other work colleagues in the Department of Medicine at TU Dresden! Very grateful for their expert insights. University of Sydney Sydney Health Charles Perkins Centre
Really looking forward to present Grand Rounds at my alma mater in Cork University Hospitals UCC Ireland University of Sydney Sydney Health Central Syd Cardio Charles Perkins Centre
Was an honour to present the Grand Rounds at Cork University Hospital, Chaired by my mentor Prof Noel Caplice UCC Ireland Central Syd Cardio Sydney Health
Delighted to share our new work optimizing protocols aimed to overcome limitations in current murine HFpEF models, improve reproducibility, and enhance clinical relevance. Huge thanks to Bailey McIntosh for this innovative tour de force. biorxiv.org/content/10.110… Yen Chin Koay
The heart IS a ketogenic organ! Specifically, HMGCS2 is critical for normal lipid metabolism and mitochondrial function, and its dysregulation contributes to HFpEF. Very proud of my team! ahajournals.org/doi/abs/10.116… Charles Perkins Centre Sydney Health University of Sydney
Kaoy et al found #HMGCS2 mediates the therapeutic effects of #NAD+ therapy in #HFpEF by restoring normal lipid metabolism & improving mitochondrial function in the heart. ahajrnls.org/4k2nj9b Yen Chin Koay John O'Sullivan Ashish Misra Chenchenwenwen
Very excited to share our latest work in the European Journal of Heart Failure detailing the energetic remodelling after mechanical unloading post LVAD in human heart failure, with identification of an important new immunometabolic pathway. Sydney Health onlinelibrary.wiley.com/share/XEBCK2H2…
Incredibly proud that our discovery has been deemed a breakthrough by Nature Cardiovascular Research in their Research Highlights rdcu.be/eqdQa Sydney Health #charlesperkinscentre #RPAH #BairdInstitute
