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The outlook for new orders from NY Fed regional manufacturers literally hit the lowest level in the history of the survey. (HT: Omair Sharif)

Fixed it: --> last year, the U.S. sold more educational services to the rest of the world than it sold in natural gas and coal **combined** --> every $1 of research funded by NIH generates $2.56 in economic activity --> more than 1.1M foreign students come to the U.S. each year

This is something bootstrappers (should) know intimately! At our last business, $ constraints forced prioritization, ROI analysis, and deep intention and mindfulness across our investments in people, infra, etc.. It's a mindset I've internalized.

I attended a vibe coding hackathon recently and used the chance to build a web app (with auth, payments, deploy, etc.). I tinker but I am not a web dev by background, so besides the app, I was very interested in what it's like to vibe code a full web app today. As such, I wrote

Money can’t Buy Days like this 🥹🙏🙏

all of DOGE should’ve been stuff like this

Armand Domalewski this is exactly what 18F was doing across the federal govt before Trump killed the group a few months ago

I designed Dropbox's storage system and modeled its durability. Durability numbers (11 9's etc) are meaningless because competent providers don't lose data because of disk failures, they lose data because of bugs and operator error. Yes S3 has lost data. No it wasn't because

I’ve spent two decades studying how brains age. And I’ve never seen anything quite like this. In normal aging, some neurons die—but it’s gradual, region-specific, and the brain compensates remarkably well. Most of what we see is driven by loss of synaptic connections, not

“Describe your childhood.” My childhood:

x.com/i/article/1931…

RFK Jr. went on national TV and spouted egregious, dangerous falsehoods about vaccines. As a parent and infectious diseases doctor, I couldn't stay silent. Fox News might not fact-check him, but I will. I've reviewed the trials. I've catalogued them. I have receipts. 🧵

Today, I’m launching a deeply personal project. I’m betting $100M that we can help computer scientists create more upside impact for humanity. Built for and by researchers, including Jeff Dean & Joelle Pineau on the board, Laude Institute catalyzes research with real-world impact.

Study by my genius friend to CURE DEAFNESS cancelled because, I shit you not: "Research programs based primarily on artificial and non-scientific categories, including amorphous equity objectives, are antithetical to the scientific inquiry". Decel anti-science brain-dead take.