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71,466 pt-level M/A from COMBINE AF shows adjusted risk of MI higher with PAF than non--paroxysmal AF, but risks of ischemic stroke and CV death lower with PAF than non-PAF Robert Giugliano #AHA24

In contemporary CICUs, target temperatures for comatose cardiac arrest patients have shifted towards normothermia since publication of the TTM2 Trial. Robert Ariss David Berg Critical Care Cardiology Trials Network #AHA24

Inopressors (particularly norepi) are the most frequently utilized vasoactive agents in CS; however, several factors including CS etiology drive differential practice patterns for vasoactive selection. @sidpatelmd #AHA24

New data from the Critical Care Cardiology Trials Network & @UmichCVC shows significant variation in vasoactive medication use in the treatment of cardiogenic shock across different CICU centers. 23% of variation was explained by local institutional practice alone. @davyhamilton1 @sidpatelMD #AHA24

In this Critical Care Cardiology Trials Network analysis, pts w/CS & isolated RV congestion had worse presenting severity of shock, ⬆️use of CICU resources, ⬆️CICU mortality. These findings support prognostic utility of recognizing pts with an isolated RV congestive profile Gurleen Kaur, MD @ebohula #AHA24

In an analysis of pts w/cardiogenic shock from the Critical Care Cardiology Trials Network registry, PAHR (HR*RAP/MAP) was strongly associated with in-hospital mortality and outperformed traditional hemodynamic metrics David Berg Curt Ginder #AHA24

In the first look at the AHA CS Registry, clinician-assigned SCAI staging effectively stratified risk of mortality in patients with CS, supporting clinical translation of SCAI staging to a broad CS population. David Berg American Heart Association #AHA24

Drs. Eugene Braunwald, Robert Giugliano and Marc Sabatine are named on the 2024 Clarivate Highly Cited Researchers List Robert Giugliano clarivate.com/highly-cited-r…

Simply amazing to learn from Dr. #Braunwald about his incredible decades of work #BWH Grand Rounds. Myocardial oxygen consumption, fibrinolysis in #MI, formation of the TIMI Group, and many more… 🫀Brigham and Women’s Research Brigham and Women's Hospital Brigham & Women's CV Fellows TIMI Study Group #Thrombosis

Brigham and Women’s Research Brigham and Women's Hospital Brigham & Women's CV Fellows TIMI Study Group And now Dr. #Sabatine showing the decades of progress in TIMI Study Group #RCTs.

#MarcSabatine David Berg #ChristianRuff Nicholas Marston #DavidMorrow Sid M. Patel Stephen Wiviott Michelle O'Donoghue #SabinaMurphy #BenScirica Brian Bergmark Erin Bohula Robert Giugliano #EugeneBraunwald #AHA24

Drs. Eugene Braunwald and Marc Sabatine giving Cardiovascular Grand Rounds Brigham and Women's Hospital on the 40th anniversary of the TIMI Study Group. timi.org/timis-40th-ann…

Coverage in TCTMD of Prakriti Gaba and Michelle O'Donoghue 's article on Lp(a) levels over time in the OCEAN(a)-TIMI 67 trial. tctmd.com/news/lpa-can-v…

Thought your Lp(a) level was stable over time? This month in JACC Journals, we showed that there is considerable intraindividual variability in Lp(a) levels among pts with ASCVD and elevated baseline Lp(a) Michelle O'Donoghue Marc Sabatine TIMI Study Group jacc.org/doi/10.1016/j.…

Does exposure to very-low levels of LDL cholesterol, achieved via PCSK9 inhibition and statin therapy, lead to cognitive decline? 👇

Drs. Eugene Braunwald and Marc Sabatine recap the first 40 years of the TIMI Study Group in this article out now in Circulation ahajournals.org/doi/10.1161/CI…

A round-up of press coverage of AZALEA-TIMI 71 primary results Robert Giugliano Sid M. Patel #abelacimab massgeneralbrigham.org/en/about/newsr…

Does the CV benefit of evolocumab differ in patients with autoimmune or inflammatory diseases? The answer lies at the intersection of dyslipidemia and inflammation. A 🧵 on our new Circulation paper. (1/10) Link: ahajournals.org/doi/abs/10.116… TIMI Study Group Robert Giugliano

André Zimerman TIMI Study Group Robert Giugliano Brittany Weber ana laura kunzler Wow! Great work Andre Brittany and team!

Coverage in NEJM Journal Watch of André Zimerman's analysis of #evolocumab in patients in FOURIER TIMI 59 with autoimmune or inflammatory disease. Robert Giugliano jwatch.org/na58726/2025/0…