Don't leave AI to the STEM folks. They are often far worse at getting AI to do stuff than those with a liberal arts or social science bent. LLMs are built from the vast corpus human expression, and knowing the history & obscure corners of human works lets you do far more with AI

"Milestones in cheminformatics" jcheminf.biomedcentral.com/articles/10.11…

#cheminformatics and #peptide informatics ppl - is anybody aware of open source or commercial tools, other than ChemDraw, that can render HELM strings as connected monomers (ie not the usual atomistic depiction)? #visualization

a core tension in applying "virtual cell" models to therapeutic development is the mismatch between the scale at which we measure biology and the scale at which we intervene. we often measure at the cell level (eg single-cell RNA-seq), but we treat at the tissue or organ level

Yiping Lu everyone always asks who/what is adam. never how is adam

Where are you mentally?

Switching from an afternoon of data typology to mixology

Andrew Kern Isaac Yonemoto is cooking Jake Wintermute 🧬/acc And so I think we come back full circle to Jake Wintermute 🧬/acc's point - it's not AI/ML alone, it's AI as a _tool_ working on synergy with biological experiment to help us understand. Because the world out there is weird and sometimes you just gotta do the experiment.

This paper is really elegant and beautiful. Researchers took a vesicle, filled it with a single type of enzyme and some protein pores, and showed that this "minimal cell," made from just three components (!!), could "actively propel itself toward an enzyme substrate gradient."

A ramble around a reservoir #cycling

TYPES OF CAT ENGINES

How many fucking options does one really need to order a coffee?

Phew! For a second I thought we were going to have to give up on ECFP’s #cheminformatics #machinelearning

#computational science -> computational results And that means scientific #data management (esp when we tie it to external sci data) If you're interested in working w/ data across chemistry, genomics, imaging and more, come and work with me vrtx.wd501.myworkdayjobs.com/Vertex_Careers…

When Buzz Aldrin passes away, he should be honoured by an international Aldrin's Law, making it legal to punch moon landing deniers in the face.

#dataviz

Happy Skynet Day

Danielle Fong 🔆 Poincaré famously only worked four (focused) hours a day. If a person really thinks they can be more effective than that man ...