We are excited to share our new paper – “IL-17RA signalling modifies cardiovascular disease risk in JAK2 clonal haematopoiesis” published in European Heart Journal  🧬🫀 1/n academic.oup.com/eurheartj/adva… Alex Bick Yash Pershad Vanderbilt University Medical Center EHJ Editor-in-Chief

Our latest work is out in Nature today. In this paper, we introduce an improved version of NanoSeq, a duplex sequencing protocol with <5 errors per billion bp in single DNA molecules, and use it to study the oral somatic mutation landscape in >1000 people. nature.com/articles/s4158…

Our work on sperm sequencing is now published! See below for: 🧑‍🔬Scientific tweetorial 📰 Accessible articles discussing implications for aging fathers [1/3] nature.com/articles/s4158…

Genome sequencing of ~30k predominately African-ancestry individuals in the Vanderbilt biobank. Relatively few people who have disease risk variants are aware of it. medrxiv.org/content/10.110…

Now THAT is a prescribing cascade Carolyn Tan

My journey began with my father’s struggle and no clear direction in sight. Growing up, he lived with debilitating ankylosing spondylitis. And in Nepal at that time: → I didn’t know rheumatologists existed. → Orthopedic doctors treated everything, so that’s who he saw. →

In this cross-sectional study of family physicians, fewer than 15% of respondents reported ideal interoperability experiences—defined as often obtaining, finding, and reconciling external data within their EHRs—in 2024. ja.ma/3WXymXn