
Ronan Hsieh, MD, MS
@ronanhsieh
Assistant Professor & GI oncologist at University of Washington Fred Hutchinson Cancer Center. Trials/early phase/AI/ML. GI cancers. @swog @fredhutch @uw
ID: 194517658
24-09-2010 09:57:48
557 Tweet
504 Followers
986 Following


So excited to present a case of locally advanced gastroesophageal cancer for a fun discussion with Drs. David Zhen from Fred Hutch Cancer Center and Bruce Lin at Binaytara Best of ASCO, Seattle 2025. The studies we discussed include MATTERHORN, CM577, DESTINY-Gastric04, etc., all practice


Listening to our lung cancer expert Lei Deng, MD (He/Him) making a blast in his lung cancer presentation!


Phenomenal 2nd day Binaytara Best of ASCO with interactions with colleagues/friends in broader community! Stellar speakers & team based learning! Binay Shah, MD, MHA Nicole D. Fleming MD Fred Hutch Cancer Center Mazyar Shadman, MD MPH Lei Deng, MD (He/Him) Diane Tseng Hiba Khan MD MPH Lisa Tachiki, MD Easter Ho Ronan Hsieh, MD, MS Hsieh Lab


✳️I am thrilled to share I received the David Roodman Excellence in Mentoring Award this year as well. To me, there is no better award than the success and growth of my mentees, Drs Tara Magge Meghana Singh, Urvashi Joshi UPMC Heme-Onc Fellowship Program ❗️ ✳️I would like to dedicate these awards



Outcomes of Solid Organ Transplant Recipients With Advanced Cancers Receiving Immune Checkpoint Inhibitors JAMA Oncology doi.org/10.1001/jamaon… 🔎128 studies, 343 SOTRs 👉Acute rejection: 36.2%; graft loss: 18%, lower risk w/ steroids & mTOR 👉ORR: 31% 🧐ICI my be considered in


A Real-World Experience in Pan-Tumor Testing for HER2 IHC in More Than 65 000 Solid Tumors JAMA Oncology doi.org/10.1001/jamaon… 🔎|Caris Life Sciences, Ventana anti-HER2/neu (4B5) assay 👉pan-tumor rate of HER2+:3.1% 🧐I consider Her2 testing relevant in most cancer (albeit rare in



Zanidatamab plus chemotherapy as first-line treatment for HER2-positive GC/GEJ cancer The Lancet Oncology doi.org/10.1016/S1470-… 🔎single-arm, phs 2 👉ORR 76·2% 👉mPFS 12·5 mo 👉mOS 36·5 mo 🧐Looks promising, now combo w/ ICI, phs-3 awaited ESMO - Eur. Oncology



Our meta-analysis (n=12,698) shows: Omitting 5-FU bolus from GI chemo regimens → ✔️ No difference in PFS/OS 📉 Less grade 3–4 neutropenia (OR 0.46) 📉 Less thrombocytopenia (OR 0.53) YUSUF İLHAN Yakup Ergün OncoDaily OncoAlert LARVOL


NIVO + IPI vs NIVO for MSI-H/dMMR mCRC: Health-related quality of life analysis 🔎CheckMate 8HW 👉mPFS clearly improved 👉 HRQoL, less symptoms 🧐 Supports use of Nivo IPI as 1st line treatment in MSI CRC #ESMOAmbassadors #ESMOGI25 ESMO - Eur. Oncology




🚨ACCORD Trial🚨 Resected Extrahepatic CCA or Gallbladder CA 🔍Randomized Adjuvant CRT + Camrelizumab vs Observation 🔥Whopping improvement in OS and RFS with CRT + ICI with persistent separate at tail of the curve!!! tinyurl.com/64yc3uum JAMA Oncology



✳️Excited to share our paper with Dr Richard Kim ❗️ In this paper, we summarized and elaborated on predictive biomarkers of immunotherapy for patients with colorectal cancer❗️ #CRCTrialsChat COLONTOWN PALTOWN Foundation Fight Colorectal Cancer Few take-home messages 👇 shorturl.at/YWI76



Dr Amol Akhade Also, 2 practical clinical pearls. 🧬MET is not uncommon in patients with Cancer of Unknown Primary (CUP) that end up being #cholangiocarcinoma. 💊Crizotinib while approved for ALK and ROS1 fusions, it’s actually a good MET⛔️too. Cholangiocarcinoma Foundation OncoAlert 🔗link.springer.com/article/10.100…
