"Peer review...for centuries the standard tool to determine an academic paper’s suitability for publication". nature.com/articles/d4158… No. The term is only a few decades old and Nature itself didn't it routinely until the 1970s. 1/3

Check out our work on fibroblast activation patterns in HF models! Huge thanks to my co-lead Laura Wienecke 🙏 from Leuschner Lab!

For those interested in repurposing factor models for patient-level comparisons and inference of multicellular programs have a look at the great overview given by Leo of the foundation work and the applications/packages that we have built! Thanks for this 😊

Posting a preprint only after your paper is rejected by a journal is not the way to do it..

👉Consider joining us for a post-doc at EMBL-EBI & AstraZenecaUK as part of the EAZPOD program to study multicellular mechanisms associated with #cancer treatment resistance! #postdoc ebi.ac.uk/research/postd…

"When I suggested the data were uninterpretable given the sample size and methods, she responded that the journal had an Impact factor in the high 30s (suggesting that regardless of my opinion, it was worth attention)" journals.biologists.com/jcs/article/13…

STAMP is OUT! Sequencing-free #singlecell RNA and Protein profiling. Game-changing approach for scalable and cost-efficient analysis of single cells. The future starts today! Amazing ⁦Luciano Martelotto 🛠🧬💻🇦🇺⁩ ⁦Dr. Jasmine Plummer 👩🏻‍🔬🧬🇨🇦🇺🇸⁩ biorxiv.org/content/10.110…

🚀 Exciting postdoc opportunity in collaboration with AstraZeneca. Our EAZPOD fellowships push the boundaries of cutting-edge computational biology in oncology. Combine method development & modelling with preclinical multiomics data. Find out more 👇 ebi.ac.uk/research/postd…

🚀 Excited to share our new publication in Nature Biotechnology! We explore scalable strategies for phenotypic screening using innovative methods with to address the challenges when the number of candidates is simply too large. Check out the details tinyurl.com/5f8vjhpp! (1/10)

And they cost ~1% of journal articles (~0.01% of research). So whatever you think of peer review (we need more vs less vs different vs none), supporting a mechanism that provides rapid and universal free access to knowledge should be a no-brainer journals.plos.org/plosbiology/ar…

"Several members of my faculty [told] me, 'You can't get a job at Berkeley without a Cell, Science or Nature paper'. These [same] people had gotten jobs at Berkeley without a [CNS] paper...We believe this to be true to an extent that's irrational" Michael Eisen youtube.com/watch?v=lg0-IR…

Kidney fibrosis as a molecular process is poorly understood. In this new study together w/ Pepperkok lab @EMBL, we present a time-resolved #multiomics + computational network modeling approach in combination w/ phenotypic assays to study #kidneyfibrosis tinyurl.com/multiomicsCKD

How good is our understanding of signaling pathways? In this study together w/ Savitski Lab @EMBL, we combine multiple state-of-the-art resources to evaluate signaling pathway inference using phosphoproteomics and kinase-substrate networks tinyurl.com/2n43jsc4

Starting today as a Staff Scientist at EMBL-EBI! I will continue my work Saez-Rodriguez Group on multicellular processes with multi-scale omics. Excited to join the Genome Campus community and see where the science takes us! ☺️ Happy to catch up with friends and colleagues in Cambridge.

📢 Introducing CORNETO: a unified, knowledge-driven framework for multi-sample network learning & modeling via constrained optimization, supporting a wide variety of network methods and prior knowledge 💻Code: github.com/saezlab/corneto 📜Paper: doi.org/10.1101/2024.1… 🧵👇

Our work with Lucas Schirmer in multiple sclerosis (MS) is out today in Nature Neuroscience. We investigated lesion progression and cell-cell communication events in MS using snRNA-seq and spatial transcriptomics 🧠 See below ⬇️ nature.com/articles/s4159…

I made a genomic scientists trained in Mexico 🇲🇽 starter pack. I'd like for our voices to be heard! If you can help spread the word, that'd be great! Thank you! ComunidadBioInfo NNB-UNAM Red Mexicana de Bioinformática LCG UNAM LCG UNAM CCG UNAM Instituto de Biotecnología UNAM LIIGH

I'm thrilled to share with you that #visiumStitched led by Nick Eagles has now been published Our #RStats / Bioconductor 📦provides a framework for stitching together multiple #Visium @10xgenomics capture areas together doi.org/10.1186/s12864…