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Thank you to Callum Thomas and the team at University of Derby for their work on this paper. So glad to be involved with getting answers to this awful condition. #LongCovid

One of the trial designs that has been cropping up in discussions recently is the cluster randomised crossover, or CRXO, design. But when is it best used & what are the key issues to look out for? 1/7 #MethodologyMonday #119

Do you have Long Covid & 18-80 years old? The University of Leicester are running a clinical trial in the UK to see if an anti-inflammatory drug helps people with Long Covid feel better. If you are interested in taking part contact [email protected] Long Covid Support 🌍 #LongCovid

Amazing fundraiser James talks about his partner’s #LongCovid experience: “She went from being an incredibly active runner, cyclist & highly competitive dinghy sailor (winner of 2022 RS Eurocup - RS200) to having to use a wheelchair to get around her home.” #CureLongCovid ⬇️

The JLA James Lind Alliance is recruiting Advisers. It's a fantastic and rewarding role, and a great opportunity for independent facilitators with an interest in supporting patient/clinician partnerships. Apply here: jla.nihr.ac.uk/news/jla-now-r…

Another super cluster crossover trial at #CCR25 - the FLUID trial (looking at Ringers lactate vs normal saline - at the system level). 1/3 See paper here … nejm.org/doi/full/10.10…

The Institute for Fiscal Studies says health spending in England will rise more slowly over the next few years than during the previous two parliaments. DHSC annual budget set to rise by 2.8% in real terms.Ave 3.5% 2019/20 to 2023/24 and 3.6% 2017/18 to 2019/20

One of the primary reasons for using a composite outcome is trial efficiency - you can get more events quickly compared to the individual components thus increasing precision and efficiency in sample size calculations 2/9 jamanetwork.com/journals/jama/…

Help future research into perinatal mental health focus on what matters to you. Find out more about this survey from NPEU-Oxford and James Lind Alliance.

In response to my question 'What do you see as the most promising medications for neuro-inflammation in ME'? Dr Claire Taylor wrote a brilliant thread Unfortunately the order was all scrambled, so with the help of ChatGPT have tried to put it in the correct order! 🧵1/n

This is pretty amazing. Rent out air purifiers for free in Edinburgh. For prevention of Covid-19 but also good for pollution too. What’s not to like 🤷🏻‍♀️ Great effort.

1/ 🧵 Key points from Long COVID Physio & WorkingAndNotWorkingWithLongCovid joint response to UK #PathwaysToWork Green paper consultation. This was an evidence based submission with shared lived experience & insights gathered over the last five years #LongCovid x.com/JCeoltaSmith/s…

This is so exciting! Water in Paris is publicly owned - what a success story! 🎉💧🎉💧🎉💧

"The Efficacy and Mechanism Evaluation (EME) Programme is accepting full applications for research looking into the treatment and management of post-acute infection syndromes and associated conditions, inc #longCOVID and #MECFS" nihr.ac.uk/funding/post-a…

The British Library has published a second blog about Donald Michie, an artificial intelligence (AI) pioneer who founded the first department for machine intelligence in the world at the University of Edinburgh. blogs.bl.uk/science/2025/0….

Neuropsychiatric symptoms often persist longer than other long covid symptoms and pose considerable burden on individuals. This review provides an assessment of the consequences, severity, and trajectory of neuropsychiatric long covid sequelae bmj.com/content/390/bm…

Sir Kenneth Calman was an outstanding Chief Medical Officer for Scotland and then England. He was a great leader and reformer in public health and academia as well as undertaking wider public service. He was also a lovely man, courteous to all. bbc.co.uk/news/articles/…

Great to see this research being shared across the news today: Health DIY tests often inaccurate, study says (via BBC News (UK)) bbc.co.uk/news/articles/…

I did promise that we would tell you what we found when we went shopping in Birmingham for self-tests. It was more work than we thought - two papers Direct-to-consumer self-tests sold in the UK in 2023: cross sectional review of regulation and evidence of performance | The BMJ

Here are the results of my LDN Experience Survey with 130 participants. If you’ve had any experience with LDN—good or bad—please take the survey linked in the quoted post. I’m planning to prepare similar surveys for other “popular” medications in our community. I’d love to create