🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

thought I ought to make a couple of xeets(?!) about flow.bio! a project >10 years in the making, now greatly expanded and improved by Goodwright & the advent of Nextflow and nf-core biorxiv.org/content/10.110…

New BioRxiv paper on using cryptic splicing to unlock precision gene therapy activation for ALS, FTD & other TDP-opathies! Key contributions Max Z. Y. J. Chien Josette Wlaschin +many others from Claire Le Pichon ule_lab FrattaLab labs and more. A thread 🧵 1/13 biorxiv.org/content/10.110…

My lab Max Delbrück Center is looking for a PhD student (fully funded) in RNA biology and data science, to investigate how oxygen regulates the formation of phase-separated condensates in the cell, and controls physiological responses!! #PhDposition mdc-berlin.de/career/jobs/ph…

dear #teamtomo, I am looking for tutorials for #relion 5 processing pipeline! if anyone is willing to share I'd be very happy!

Can MS2 loops stall reverse transcription? Does anyone know? I'm using Superscript IV at 50C.

Flora is an awesome scientist! You should work with her.

We're looking for someone with a creative mindset and excellent modern molecular biology skills (DNA manipulation, Illumina, Nanopore etc) to join our team at UCL and The Crick in the FrattaLab developing candidate gene therapies for ALS. Apply here: jobs.ac.uk/job/DGJ551/res…

Opportunity of a lifetime! Apply immediately.

We are excited to share our latest insights into human mRNA export. Pre-print: biorxiv.org/content/10.110…; tweetorials below and x.com/HohmannUlrich/… by the exceptional Ulrich Hohmann, who led the project in a joint effort of the Plaschka Lab and @JuliusBrennecke labs. (1/7)

The next interview in our series "IMPloyable talent" features Farja Ayala Muñoz, recent PhD graduate from the Plaschka Lab. Farja is a skilled biochemist, #opentowork in Vienna, & seeking industry roles. Get to know her: imp.ac.at/career/beyond/… Vienna BioCenter, Vienna BioCenter Scientific Training

How can cellular signalling swiftly & selectively remodel the transcriptome to drive biological transition? How this switch is orchestrated has been a mystery... 🧵 nature.com/articles/s4159…

Our paper on cryptic splicing-controlled protein expression, which we hope will inspire safer and more adventurous gene therapy approaches for ALS and FTD, has been published in Science Magazine science.org/doi/10.1126/sc…

Come and explore the mechanisms of gene expression with us! We are hiring two postdocs in cryo-EM and - with Francisco Balzarotti - in super-resolution microscopy. 👉imp.ac.at/career/open-po… 👉imp.ac.at/career/open-po…

We are very excited to share our recent preprint on the nuclear import mechanism of the proteasome, driven by the multivalent adaptor AKIRIN2! biorxiv.org/content/10.110… 🧵 (1/7)