
Sack-Yarov Lab
@sackyarov
Studying new methods to observe and control electrophysiological signaling #ucdavisresearch
ID: 1091042277533732865
https://basicscience.ucdmc.ucdavis.edu/Sack_and_Yarov-Yarovoy_Labs/ 31-01-2019 18:35:24
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184 Followers
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The Yarov-Yarovoy Lab is still going strong on the last day of #bps2020! Stop by B416 and hear about our work! Rosetta@Home Biophysical Society #bps20 UC Davis Research UCDavisMedSchool



I hope to see not only reflection, but also action and change UC Davis. MCIP at UC Davis UC Davis Biomedical Engineering Graduate Group UCD Biophysics PTX at UC Davis #StrikeforBlackLives #ShutDownSTEM #ShutDownAcademia #BlackLivesMatter

We are making an exciting progress! #NIH #nihHEALinitiative @NINDSNews NIH Pain Research #scientists at UCDavisMedSchool are using computational biology to engineer a tarantula venom #peptide into a non-opioid treatment for #chronicpain. #NIH #nihHEALinitiative heal.nih.gov/news/stories/p…


We are SO deeply grateful to Dr. Rabaud for her purposeful and persistent work with MCIP at UC Davis and now also UCD Biophysics Thanks Nicole for sharing your inspiring story and for your long lasting impact on improving the graduate student (and faculty) experience!



Matthew James Marquis and Jon Sack Sack-Yarov Lab show that the use-dependent inhibition of Kv2.1 by RY785 is consistent with gated access to a cavity within the channel that traps RY785. bit.ly/36rFYuE #Biophysics #MolecularPhysiology #MolecularPharmacology


Honored and grateful to host the incredible Nieng Yan for the UC Davis Tracy and Ruth Storer Lectureship in the Life Sciences this week! Biological Sciences UC Davis Health UC Davis Physiology UC Davis Pharmacology Sack-Yarov Lab


Mechanism of use-dependent Kv2 channel inhibition by RY785 rupress.org/jgp/article/15… Nice paper from the Sack-Yarov Lab lab!

Image shows how RY785 modifies gating currents. Marquis and Sack Sack-Yarov Lab show mechanism of use-dependent Kv2 channel inhibition by RY785. bit.ly/36rFYuE #Biophysics #MolecularPhysiology #MolecularPharmacology


Marquis & Sack-Yarov Lab bit.ly/36rFYuE show that voltage activation, but not channel opening, is required for RY785 to access the central cavity of Kv2 channels, where it promotes voltage sensor deactivation to trap itself in place. In Research News: bit.ly/3KK7EsM


A Kv2 inhibitor traps itself in place. Our latest Research News highlights study (bit.ly/36rFYuE) from Matthew James Marquis and Jon T. Sack Sack-Yarov Lab: bit.ly/3KK7EsM


🚨 Check out this work from Department Faculty Sack-Yarov Lab! 🚨

Marquis & Sack Sack-Yarov Lab (bit.ly/36rFYuE) show that voltage activation, but not channel opening, is required for RY785 to access the central cavity of Kv2 channels, where it promotes voltage sensor deactivation to trap itself in place bit.ly/3KK7EsM


Congratulations to Dr. John Dawson from UCD Biophysics & UC Davis Physiology, who has been working with me, Prof. Colleen Clancy @clancyatheart and Prof. Yarov-Yarovoy Sack-Yarov Lab! John conferred Ph.D. degree in Biophysics in May and had a great exit seminar today!



Excited to share the new paper co-authored with Igor Vorobyov, @clancyatheart, Sack-Yarov Lab, Kazuharu Furutani entitled "Structural modeling of the hERG potassium channel and associated drug interactions" frontiersin.org/articles/10.33…