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Taking a deep dive into the mystery of #fibrostricturing #CD! Big collaborative effort with Gianluca Matteoli Saeed Bo-Jun Ke and many other collaborators! Severine Vermeire Bram Verstockt Sare Verstockt andre dhoore Gabriele Bislenghi FWO TARGID KU LEUVEN Helmsley Charitable Trust

Our study sheds light on fibrostenotic #CrohnsDisease! Together with IBD Leuven we uncover pro-fibrotic signals from CD150-monocytes, leading to a specific fibroblast population causing inflammation & tissue fibrosis. Follow our FIBROTARGET Horizon Europe 🇪🇺 consortium for new update

Really nice study - progress in an area of unmet need in #IBD

Another #DDW2023 poster session round today! Proud of the entire team presenting their research today, disseminating with the #IBD field! #IDeGreef #LFierens Severine Vermeire João Sabino Bram Verstockt #MFerrante Helmsley Charitable Trust TARGID KU LEUVEN

📚For Tomorrow's #JournalClub Tapas Mukherjee UofT Immunology will present a #preprint by Gianluca Matteoli Severine Vermeire labs on how CD150 monocytes promote tissue fibrosis by inducing the differentiation of FAP fibroblasts in Crohn’s disease patients💥👇 biorxiv.org/content/10.110…

Our new article, "IL-1R signaling drives enteric glia-macrophage interaction in colorectal cancer progression" is now available as preprint biorxiv.org/content/10.110… fantastic collaboration between our lab Gianluca Matteoli TARGID KU LEUVEN and the lab of @ProfSvenWehner Rheinische Friedrich-Wilhelms-Universität Bonn

Today our Human Lung Cell Atlas (HLCA) paper came out in Nature Medicine nature.com/articles/s4159…! The HLCA includes 2.4M cells from 486 individuals and 49 datasets. Check out this tweetorial to learn more about how we built it, and how you can use it (1/21)

It’s truly a pleasure hosting this week #Victoria #Gudiño from the Azucena Salas lab IBD lab giving an excellent talk today at our weekly labmeeting! #unmetneeds #perianalCD Gianluca Matteoli FIBROTARGET Helmsley Charitable Trust

Exciting news!! IBD Leuven IBD Leuven , Gianluca Matteoli and Boeckxstaens Lab , has secured a $2.8m grant from Helmsley Charitable Trust for a collaborative study on the origin of fibrosis in Crohn's disease. shorturl.at/dfMW3 Bram Verstockt Severine Vermeire

Excited to announce our latest article on enteric glia-macrophage communication in colorectal cancer (CRC) now published in Nature Communications! doi.org/10.1038/s41467…

Our study "Intercellular interaction between FAP+ fibroblasts and CD150+ inflammatory monocytes mediates fibrostenosis in Crohn’s disease" is out jci.org/articles/view/… with first authors Bo-Jun Ke and Saeed in collaboration with Severine Vermeire and the IBD Leuven team

As we say in India, a 'double Dhamaka' from Mucosal Immunology Lab. Super happy to be part of this study co-lead by the amazing @LiesvanBaarle @VeronicaDeSimone alongside Linda Schneider from Rheinische Friedrich-Wilhelms-Universität Bonn

Intercellular interaction between FAP+ fibroblasts and CD150+ inflammatory monocytes mediates fibrostenosis in @CD, a fantastic collaboration with Gianluca Matteoli with first authors Bo-Jun Ke Saeed now in Journal of Clinical Investigation jci.org/articles/view/… Severine Vermeire