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Our recent take on localized #GPCR signaling Nina Tsvetanova Miriam Stoeber @bradenlobingier nature.com/articles/s4158…

Happy to contribute in the study!! Progressive obesity leading to diabetes can show key cellular and molecular alteration in islet microenvironment.

Thrilled to have been part of this monumental project with great collaborators! Check out the thread below to learn how dynamic the mighty pancreatic islets are during the progression of obesity #obesity #diabetes #singlecell

We are thrilled to share the preprint from our first venture in constructing a cell type #atlas - a #multiomics atlas for #murine #pancreatic #islet remodeling during #hyperglycaemia progression (1/n) #scRNAseq #MetabolicDisorder biorxiv.org/content/10.110…

Online now: Biased agonism of GLP-1R and GIPR enhances glucose lowering and weight loss, with dual GLP-1R/GIPR biased agonism yielding greater efficacy dlvr.it/TL8Kbz

State-dependent central synaptic regulation by GLP-1 is essential for energy homeostasis go.nature.com/3HrcD5J

Firing up adipocytes! jci.org/articles/view/… Chih-Hao Lee & team discover IL-13 signaling in preadipocytes promotes beige adipogenesis and contributes to body weight maintenance and glucose metabolism in mice.

New content online: Diabetes mellitus and the key role of endoplasmic reticulum stress in pancreatic β cells bit.ly/3ZhpTzR

IL-13 priming in precursors drives beige adipogenesis and enhances metabolic homeostasis: jci.org/articles/view/… Margo P. Emont and Jun Wu provide a Commentary on Yesian et al. (jci.org/articles/view/…)

New content online: Tirzepatide differentially affects body weight in mice and humans bit.ly/3FJ175e

Development of Mutant M3 Muscarinic Receptors Biased for G Protein Activation or Recruitment of β-Arrestins | Biochemistry pubs.acs.org/doi/10.1021/ac…

Now online! The microbiome diversifies long- to short-chain fatty acid-derived N-acyl lipids dlvr.it/TLHnnL

Testing the carbohydrate-insulin model: Some aspects are consistent, but overall the data do not support the model dlvr.it/TLJ34q

New! Online now: Genetic and physiological insights into satiation variability predict responses to obesity treatment dlvr.it/TLJxNz

For a long time, researchers were waiting for the call of the erstwhile SERB's PI-driven Core Research Grant. The wait is finally over. ANRF now announces a much better and restructured version with more flexibility and enhanced funding. The Advanced Research Grant (ARG) call

Online Now: Mitochondrial innate immune signaling in skeletal muscle adaptation to exercise dlvr.it/TLLvk5 #trends #endocrinology #metabolism

#StopObesity | Obesity can lead to severe health issues! But the good news? You can take control of your health at any time. Small lifestyle changes can make a big difference. Choose health today for a better tomorrow. #HealthForAll

A man with a severe speech disability is able to speak expressively and sing using a brain implant that translates his neural activity into words almost instantly. go.nature.com/405JUcW