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Very excited and honored to have been named a Beckman Young Investigator!

This week we are highlighting Dr. Tony Mustoe. The Mustoe lab focuses on developing & applying chemical probing technologies to measure RNA structure in cells & its role in RNA function. More about their recent discovery of a structural switch the 7SK RNA: bit.ly/3qPqabv

We are thrilled to have hosted our first annual “Science and Sip” THINC poster session! Congratulations to our trainee winners Ashley (Hayden) Monahan, PhD Ashley Hayden from @AreyLab, Courtney Chambers Courtney Chambers from H. Courtney Hodges and Ritwika Bose from the lab of Tony Mustoe!

Congratulations to Kishor Bhakat, PhD and Vimla Band, PhD on their recently announced funding from the Congressionally Directed Medical Research Program - Breast Cancer

Excited to share the latest study from my lab led by a fantastic graduate student shalini rawat showing that "RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes" published online today in Journal of Cell Biology rupress.org/jcb/article/22… #lysosome

30?? I'm almost 40.

Proud mentor moment. Feeling proud to announce shalini rawat is one of the three chosen recipient of #Saroj Chandrasekhar memorial award 2023 for her PhD work. Many congratulations Shalini...keep making all of us proud, this is just a start! Dept. of Biological Sciences (DBS), IISER Mohali IISER Mohali Journal of Cell Biology

Many congratulations shalini rawat Keep it up...rupress.org/jcb/article/22… Journal of Cell Biology

Congratulations to Dr. Lolitika Mandal Lolitika Mandal and Dr. Mahak Sharma Mahak Sharma for getting featured as future hopes in the prècis published by Vigyan Prasar Vigyan Prasar on 75 women trailblazers of science. 🎊

Mutation signature filtering enables high-fidelity RNA structure probing at all four nucleobases with DMS NAR academic.oup.com/nar/advance-ar…

For all those interested in performing this analysis using the #RNA Framework, this can be achieved by passing "--only-mut 'G>Y;A>N;C>N;T>N'" to the rf-count module!

Really happy this is now out! Awesome work from David Mitchell, Jenn Cotter, and Irfana.Saleem showing that DMS can be used to probe all 4 bases in cells. Please give it a try! academic.oup.com/nar/advance-ar…

Online now! Review! Causes, functions, and therapeutic possibilities of RNA secondary structure ensembles and alternative states by Ritwika Bose, Irfana Saleem, and Tony Mustoe at THINC@BCM dlvr.it/T18pfS #chembiol

Very excited this is out! authors.elsevier.com/a/1iOw08jWWJtY…

We try to synthesize how secondary structural ensembles shape RNA function across the RNA life cycle. This ensemble view provides new ways to understand and target disease, complementing other excellent recent reviews from Danny IncaRNAto Robert Spitale, Al-Hashimi & others

Kudos to co-first authors Ritwika Bose and Irfana.Saleem!

Very excited to share my first publication with Irfana.Saleem and Tony Mustoe reviewing causes, functions, and therapeutic possibilities of RNA secondary structure ensembles! sciencedirect.com/science/articl…

Francis Crick sent this letter to Nature to appeal a rejection. Regardless of whether Crick was right about the importance, the arguments lack substance; they focus on authority. Whether someone is getting married (or not) or making a visit (or not) is not relevant. Via

Simultaneous mapping of RNA secondary, tertiary, and quaternary structure in living cells by multi-site DMS probing biorxiv.org/cgi/content/sh… #biorxiv_biochem