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I wrote about the National Institutes of Health and the various serious and unserious proposals for NIH reform that have been floating around. It is important to understand how this agency actually functions and point criticism at the right problems. A short 🧵:

Towards the #AI virtual cell, which would represent one the most extraordinary achievements in life science cell.com/cell/fulltext/… Cell Stephen Quake Chan Zuckerberg Initiative CZI Science Charlotte Bunne

Surreal! 🤩 Along with Martin Varsavsky and Dina Radenkovic / Turner, we co-founded Gameto in 2020 with just a silly graph theory algorithm I designed to predict TFs that could differentiate ovarian cells from iPSCs. 💻 Now, little Mia is here with the technology that has grown out of that

Excited to share our lab's first preprint: we used spatial transcriptomics to dissect how aging disrupts the cycling ovary! 🧵 This was an incredible team effort w/ Jennifer Garrison Tammy Lan David Fischer AlisonKochersberger Ruth Raichur Sophia Szady

It’s crazy how talking with a science buddy is simultaneously what’s most likely to move the project forward and the thing that’s least prioritized in our schedule.

This has promise to change surgery. We haven’t had a new class of painkillers for acute pain for decades. And 15,000 people died of prescription opioid overdoses in 2022. But will be interested in hearing from anyone with real world experience. bostonglobe.com/2025/01/30/bus…

A very innovative approach to cancer: engineering fat cells to convert to beige fat to starve tumors, outcompeting 5 types of cancer in experimental models nature.com/articles/s4158… Nature Biotechnology Nadav Ahituv UCSF School of Medicine

Today, we are announcing a new pre-seed venture fund – Altitude Lab Fund – to support early-stage biotech startups facing the loss of SBIR grants due to recent federal funding policy shifts which have left many biotech founders in limbo. I wrote about why these funds are so

This isn't science fiction. This is real sequencing biotechnology just introduced by Roche. Wild and wonderful.

A new gene-editing therapy may have cured a baby of a deadly metabolic disorder. By inserting a corrective gene into a 'safe harbor' of the genome, this approach aims to avoid the risks of traditional gene therapies. science.org/content/articl…

Regeneron CEO Len Schleifer on CNBC: The biotech/pharma sector should be seen as the "health defense industry" vital for global wellbeing. To sustain innovation, it needs proper support. cnb.cx/4iQSkfV

What if LLMs could “read” & “write” biology? 🤔 Introducing C2S‑Scale—a Yale University + Google AI Google DeepMind collab: we scaled LLMs (up to 27 B!) to analyze & generate single‑cell insights by turning transcriptomes into text 🧬➡️📝 🔗 Blog: research.google/blog/teaching-… 🔗 Preprint:

Opportunistic A.I. interpretation of medical scans. The list keeps getting longer of improved detection, unrelated to why the scan was obtained Today; Aortic aneurysm from breast MRI nature.com/articles/s4146… My running list👇

Excited to share that we've received an NIH R35 MIRA! This grant will support our work building tools to study how cell states change over space and time in disease. Grateful to our community, and especially the wonderful team I get to work with.