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In our latest paper Journal of Clinical Oncology, we demonstrate how inherited factors perform for risk assessment in real-life breast cancer screening data. A special focus is on a breast cancer polygenic risk score (PRS), which is a more recently identified inherited risk factor. 🙍🏽‍♀️ 117,252

Many diseases (e.g. #T1D, #rheumatoidarthritis, #IBD, #asthma) impact men and women of reproductive age. In a paper out today Rheumatology & Rheumatology Advances in Practice we asked: What is the impact of immune-mediated diseases on reproductive success and risk of maternal and perinatal outcomes? 📊 An evaluation

We are delighted to announce the publication of the #EULIFE charter of independent life science research institutes in FEBS Letters! This charter outlines 10 principles required for #researchinstitutes to flourish. Read the charter here: doi.org/mnhd @EULIFEnews

The Nordic EMBL P'ship Partnership invites applications for postdoctoral fellows through our NORPOD program! Apply for one of 7 postdoctoral positions in molecular medicine! All details: shorturl.at/ijrX5 Application deadline: 31 May 2024 FIMM HelsinkiUni @NCMMnews DANDRITE MIMS - Molecular Infection Medicine Sweden

Today, RGC has published an important paper in nature today, describing an analysis of close to a million human exomes (n=983,578) as a single variant call set (!). This is the largest and most diverse rare variant database created so far. This impressive feat is accomplished by

Do oral and non-oral lichen planus share the same genetics? Yes (20) and no (7)! Our new paper AJHG using FinnGen reveals genetic heterogeneity between the two, with differential risk for autoimmune diseases and oral cancer cell.com/ajhg/fulltext/…. 1/7

Kesällä vietetään suomalaisten kaksoskohorttitutkimusten 50-vuotisjuhlia University of Helsinki FIMM HelsinkiUni 🍾

Hurry and apply now — the first NORPOD postdoc call is closing soon, so don't miss this exciting opportunity! The core concept of the NODPOD programme is that all postdocs are supervised by two Group Leaders from the Nordic EMBL P'ship partnership, each from a different institute.

Exciting start to our scientific retreat "Fit for FIMM - the 2024 Mix" in Korpilampi! During the first session, five of our FIMM-EMBL Group Leaders captivated the audience by presenting their impressive work. Warm thanks to our sponsors for supporting the event!

Our flaghsip intervene_eu paper is now published! I think this is an important piece of work to elevate the stature of polygenic score to that of other well-studied risk factors We provide country-specific cumulative incidence estimates for 18 diseases by PGS levels.

Professor Olli Kallioniemi has been awarded a 2.5 M€ Brain Gain grant for research into artificial intelligence in medicine. The grant will allow Kallioniemi to return to Finland and establish a group FIMM HelsinkiUni HiLIFE_Helsinki gradually, during 2024-25. helsinki.fi/en/news/life-s…

It was an entertaining defence: Juulia Partanen did a great job answering essential questions by the opponent Tuuli Lappalainen

Welcome to the "Harvest time at FIMM" seminar on Oct 30! The event includes a talk by FIMM Director Samuli Ripatti, followed by presentations from the new FIMM-EMBL Group Leaders: Nina Mars, Arafath (Rafa) Najumudeen & Simone Rubinacci. Register by Oct 20: lyyti.fi/reg/FIMM_harve…

Over 40 members of the FIMM community are currently enjoying the company of our Nordic EMBL P'ship colleagues, inspiring science, and the wonderful hospitality of our sister institute @NCMMnews in Oslo. #NEPM24

We are hiring! Looking for two postdocs. Topics: a) ancestry informed polygenic scores for mixed ancestry individuals and b) integrating polygenic risk models with clinically actionable rare variants for comprehensive disease risk assessment. genomics.ut.ee/en/content/job…

Warm welcome to the Harvest time at FIMM seminar! FIMM Director Samuli Ripatti and new FIMM-EMBL Group Leaders will present their plans for the near future. 📅Wednesday Oct 30 at 13:15-15:00 🏢Biomedicum Helsinki, Lecture Hall 1 More information and registration: lyyti.fi/reg/FIMM_harve…

📣 Exciting news! Don’t miss your chance to be part of a great postdoctoral opportunity! Stay tuned for the upcoming launch of the next NORPOD Postdoctoral Programme in Molecular Medicine! 👇 tinyurl.com/NORPOD Nordic EMBL P'ship #postdoc #nordics #collaboration #EMBL #NordForsk

Exciting Postdoc Opportunity in Genomic Data Science! Work with top experts at FIMM to develop tools for genetic and clinical risk prediction as part of the international #TeamPerMed consortium. Learn more & apply by Nov 30: jobs.helsinki.fi/job/Helsinki-P… #sciencejobs #postdocjobs

A FinnGen-based study led by FIMM Group Leader Elisabeth Widén has identified a gene defect in the TBPL2 gene that affects the maturation of oocytes, leading to infertility in women who have inherited the non-functional form of the gene from both parents. helsinki.fi/en/news/genes/…

Out now! We established a platform for functional characterization of gene variants, providing insight for 315 LDLR variants. Functional data improves cardiovascular risk assessment, going beyond "pathogenic" and "benign" groups. Important for #FH sciencedirect.com/science/articl…